TY  - JOUR
AU  - Ehlting, Anne
AU  - Zweyer, Margit
AU  - Maes, Elke
AU  - Schleehuber, Yvonne
AU  - Doshi, Hardik
AU  - Sabir, Hemmen
AU  - Bernis, Maria Eugenia
TI  - Impact of Hypoxia-Ischemia on Neurogenesis and Structural and Functional Outcomes in a Mild-Moderate Neonatal Hypoxia-Ischemia Brain Injury Model.
JO  - Life
VL  - 12
IS  - 8
SN  - 2075-1729
CY  - Basel
PB  - MDPI
M1  - DZNE-2022-01436
SP  - 1164
PY  - 2022
N1  - CC BY: https://creativecommons.org/licenses/by/4.0/
AB  - Hypoxic-ischemic encephalopathy (HIE) is a common type of brain injury caused by a lack of oxygen and blood flow to the brain during the perinatal period. The incidence of HIE is approximately 2-3 cases per 1000 live births in high-income settings; while in low- and middle-income countries, the incidence is 3-10-fold higher. Therapeutic hypothermia (TH) is the current standard treatment for neonates affected by moderate-severe HIE. However, more than 50
KW  - BrdU (Other)
KW  - MRI (Other)
KW  - behavior testing (Other)
KW  - hypothermia (Other)
KW  - hypoxia-ischemia (Other)
KW  - mild HIE (Other)
KW  - neonatal (Other)
KW  - neurogenesis (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:36013343
C2  - pmc:PMC9410039
DO  - DOI:10.3390/life12081164
UR  - https://pub.dzne.de/record/165129
ER  -