% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Brunoni:165244,
      author       = {Brunoni, Andre R and Ekhtiari, Hamed and Antal, Andrea and
                      Auvichayapat, Paradee and Baeken, Chris and Benseñor,
                      Isabela M and Bikson, Marom and Boggio, Paulo and Borroni,
                      Barbara and Brighina, Filippo and Brunelin, Erome and
                      Carvalho, Sandra and Caumo, Wolnei and Ciechanski, Patrick
                      and Charvet, Leigh and Clark, Vincent P and Cohen Kadosh,
                      Roi and Cotelli, Maria and Datta, Abhishek and Deng, Zhi-De
                      and De Raedt, Rudi and De Ridder, Dirk and Fitzgerald, Paul
                      B and Floel, Agnes and Frohlich, Flavio and George, Mark S
                      and Ghobadi-Azbari, Peyman and Goerigk, Stephan and
                      Hamilton, Roy H and Jaberzadeh, Shapour J and Hoy, Kate and
                      Kidgell, Dawson J and Zonoozi, Arash Khojasteh and Kirton,
                      Adam and Laureys, Steven and Lavidor, Michal and Lee, Kiwon
                      and Leite, Jorge and Lisanby, Sarah H and Loo, Colleen and
                      Martin, Donel M and Miniussi, Carlo and Mondino, Marine and
                      Monte-Silva, Katia and Morales-Quezada, Leon and Nitsche,
                      Michael A and Okano, Alexandre H and Oliveira, Claudia S and
                      Onarheim, Balder and Pacheco-Barrios, Kevin and Padberg,
                      Frank and Nakamura-Palacios, Ester M and Palm, Ulrich and
                      Paulus, Walter and Plewnia, Christian and Priori, Alberto
                      and Rajji, Tarek K and Razza, Lais B and Rehn, Erik M and
                      Ruffini, Giulio and Schellhorn, Klaus and Zare-Bidoky,
                      Mehran and Simis, Marcel and Skorupinski, Pawel and Suen,
                      Paulo and Thibaut, Aurore and Valiengo, Leandro C L and
                      Vanderhasselt, Marie-Anne and Vanneste, Sven and
                      Venkatasubramanian, Ganesan and Violante, Ines R and Wexler,
                      Anna and Woods, Adam J and Fregni, Felipe},
      title        = {{D}igitalized transcranial electrical stimulation: {A}
                      consensus statement.},
      journal      = {Clinical neurophysiology},
      volume       = {143},
      issn         = {0921-884X},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier Science},
      reportid     = {DZNE-2022-01537},
      pages        = {154-165},
      year         = {2022},
      abstract     = {Although relatively costly and non-scalable, non-invasive
                      neuromodulation interventions are treatment alternatives for
                      neuropsychiatric disorders. The recent developments of
                      highly-deployable transcranial electric stimulation (tES)
                      systems, combined with mobile-Health technologies, could be
                      incorporated in digital trials to overcome methodological
                      barriers and increase equity of access. The study aims are
                      to discuss the implementation of tES digital trials by
                      performing a systematic scoping review and strategic process
                      mapping, evaluate methodological aspects of tES digital
                      trial designs, and provide Delphi-based recommendations for
                      implementing digital trials using tES.We convened 61
                      highly-productive specialists and contacted 8 tES companies
                      to assess 71 issues related to tES digitalization readiness,
                      and processes, barriers, advantages, and opportunities for
                      implementing tES digital trials. Delphi-based
                      recommendations $(>60\%$ agreement) were provided.The main
                      strengths/opportunities of tES were: (i) non-pharmacological
                      nature $(92\%$ of agreement), safety of these techniques
                      $(80\%),$ affordability $(88\%),$ and potential scalability
                      $(78\%).$ As for weaknesses/threats, we listed insufficient
                      supervision $(76\%)$ and unclear regulatory status $(69\%).$
                      Many issues related to methodological biases did not reach
                      consensus. Device appraisal showed moderate digitalization
                      readiness, with high safety and potential for trial
                      implementation, but low connectivity.Panelists recognized
                      the potential of tES for scalability, generalizability, and
                      leverage of digital trials processes; with no consensus
                      about aspects regarding methodological biases.We further
                      propose and discuss a conceptual framework for exploiting
                      shared aspects between mobile-Health tES technologies with
                      digital trials methodology to drive future efforts for
                      digitizing tES trials.},
      keywords     = {Consensus / Electric Stimulation / Humans / Telemedicine /
                      Transcranial Direct Current Stimulation: methods / Delphi
                      panel (Other) / Digital health (Other) / Mobile Health
                      (Other) / Non-invasive neuromodulation (Other) / Systematic
                      review (Other)},
      cin          = {AG Teipel},
      ddc          = {610},
      cid          = {I:(DE-2719)1510100},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)16},
      pmc          = {pmc:PMC10031774},
      pubmed       = {pmid:36115809},
      doi          = {10.1016/j.clinph.2022.08.018},
      url          = {https://pub.dzne.de/record/165244},
}