%0 Journal Article
%A Hermann, Peter
%A Schmitz, Matthias
%A Cramm, Maria
%A Goebel, Stefan
%A Bunck, Timothy
%A Schütte-Schmidt, Julia
%A Schulz-Schaeffer, Walter
%A Stadelmann, Christine
%A Matschke, Jakob
%A Glatzel, Markus
%A Zerr, Inga
%T Application of real-time quaking-induced conversion in Creutzfeldt-Jakob disease surveillance.
%J Journal of neurology
%V 270
%N 4
%@ 0340-5354
%C Berlin
%I Springer
%M DZNE-2023-00122
%P 2149-2161
%D 2023
%Z ISSN 1432-1459 not unique: **2 hits**.
%X Evaluation of the application of CSF real-time quaking-induced conversion in Creutzfeldt-Jakob disease surveillance to investigate test accuracy, influencing factors, and associations with disease incidence.In a prospective surveillance study, CSF real-time quaking-induced conversion was performed in patients with clinical suspicion of prion disease (2014-2022). Clinically or histochemically characterized patients with sporadic Creutzfeldt-Jakob disease (n = 888) and patients with final diagnosis of non-prion disease (n = 371) were included for accuracy and association studies.The overall test sensitivity for sporadic Creutzfeldt-Jakob disease was 90
%K Humans
%K Creutzfeldt-Jakob Syndrome: diagnosis
%K Creutzfeldt-Jakob Syndrome: epidemiology
%K Prospective Studies
%K Pandemics
%K Sensitivity and Specificity
%K COVID-19
%K Creutzfeldt–Jakob disease (Other)
%K Creutzfeldt–Jakob disease (Other)
%K Diagnosis (Other)
%K Epidemiology (Other)
%K Prion (Other)
%K RT-QuIC (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:36624183
%2 pmc:PMC9829526
%R 10.1007/s00415-022-11549-2
%U https://pub.dzne.de/record/169347