TY  - CHAP
AU  - Dörpinghaus, Jens
AU  - Weil, Vera
AU  - Schaaf, Sebastian
AU  - Apke, Alexander
TI  - Sequence Analysis; 1st ed. 2022
VL  - 112
CY  - Cham
PB  - Springer International Publishing
M1  - DZNE-2023-00417
SN  - 978-3-031-08411-9
T2  - Studies in Big Data
SP  - 415-437
PY  - 2022
AB  - The collection and understanding of biological sequences once founded bioinformatics as a scientific field, and is still the most common reception even outside the scientific community. In this chapter we introduce principles of sequence analysis, starting on the biological backgrounds, up to algorithmic concerns. In the following, we focus on the principle handling of sequence data in practice, using BioJava’s relevant packages. Further application-oriented topics treat database searches as well as the underlying sequence alignment algorithms. While we concentrate on the classical FASTA format for demonstration reasons, Next-Generation Sequencing (NGS) data and principles are addressed as well. The chapter closes on relating to contemporary developments in applications and technologies.
LB  - PUB:(DE-HGF)7
DO  - DOI:10.1007/978-3-031-08411-9_15
UR  - https://pub.dzne.de/record/257348
ER  -