%0 Journal Article
%A Perosa, Valentina
%A Rotta, Johanna
%A Yakupov, Renat
%A Kuijf, Hugo J
%A Schreiber, Frank
%A Oltmer, Jan T
%A Mattern, Hendrik
%A Heinze, Hans-Jochen
%A Düzel, Emrah
%A Schreiber, Stefanie
%T Implications of quantitative susceptibility mapping at 7 Tesla MRI for microbleeds detection in cerebral small vessel disease.
%J Frontiers in neurology
%V 14
%@ 1664-2295
%C Lausanne
%I Frontiers Research Foundation
%M DZNE-2023-00437
%P 1112312
%D 2023
%X Cerebral microbleeds (MBs) are a hallmark of cerebral small vessel disease (CSVD) and can be found on T2*-weighted sequences on MRI. Quantitative susceptibility mapping (QSM) is a postprocessing method that also enables MBs identification and furthermore allows to differentiate them from calcifications.We explored the implications of using QSM at submillimeter resolution for MBs detection in CSVD.Both 3 and 7 Tesla (T) MRI were performed in elderly participants without MBs and patients with CSVD. MBs were quantified on T2*-weighted imaging and QSM. Differences in the number of MBs were assessed, and subjects were classified in CSVD subgroups or controls both on 3T T2*-weighted imaging and 7T QSM.48 participants [mean age (SD) 70.9 (8.8) years, 48
%K 7 Tesla MRI (Other)
%K cerebral amyloid angiopathy (CAA) (Other)
%K cerebral small vessel disease (CSVD) (Other)
%K hypertensive arteriopathy (HA) (Other)
%K microbleeds (Other)
%K quantitative susceptibility mapping (QSM) (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:37006483
%2 pmc:PMC10050564
%R 10.3389/fneur.2023.1112312
%U https://pub.dzne.de/record/257557