TY  - JOUR
AU  - Perosa, Valentina
AU  - Rotta, Johanna
AU  - Yakupov, Renat
AU  - Kuijf, Hugo J
AU  - Schreiber, Frank
AU  - Oltmer, Jan T
AU  - Mattern, Hendrik
AU  - Heinze, Hans-Jochen
AU  - Düzel, Emrah
AU  - Schreiber, Stefanie
TI  - Implications of quantitative susceptibility mapping at 7 Tesla MRI for microbleeds detection in cerebral small vessel disease.
JO  - Frontiers in neurology
VL  - 14
SN  - 1664-2295
CY  - Lausanne
PB  - Frontiers Research Foundation
M1  - DZNE-2023-00437
SP  - 1112312
PY  - 2023
AB  - Cerebral microbleeds (MBs) are a hallmark of cerebral small vessel disease (CSVD) and can be found on T2*-weighted sequences on MRI. Quantitative susceptibility mapping (QSM) is a postprocessing method that also enables MBs identification and furthermore allows to differentiate them from calcifications.We explored the implications of using QSM at submillimeter resolution for MBs detection in CSVD.Both 3 and 7 Tesla (T) MRI were performed in elderly participants without MBs and patients with CSVD. MBs were quantified on T2*-weighted imaging and QSM. Differences in the number of MBs were assessed, and subjects were classified in CSVD subgroups or controls both on 3T T2*-weighted imaging and 7T QSM.48 participants [mean age (SD) 70.9 (8.8) years, 48
KW  - 7 Tesla MRI (Other)
KW  - cerebral amyloid angiopathy (CAA) (Other)
KW  - cerebral small vessel disease (CSVD) (Other)
KW  - hypertensive arteriopathy (HA) (Other)
KW  - microbleeds (Other)
KW  - quantitative susceptibility mapping (QSM) (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:37006483
C2  - pmc:PMC10050564
DO  - DOI:10.3389/fneur.2023.1112312
UR  - https://pub.dzne.de/record/257557
ER  -