%0 Journal Article
%A Klyscz, Philipp
%A Ihl, Thomas
%A Laumeier, Inga
%A Steinicke, Maureen
%A Endres, Matthias
%A Michelson, Georg
%A Audebert, Heinrich J
%T Retinal microvascular signs and recurrent vascular events in patients with TIA or minor stroke.
%J Stroke and vascular neurology
%V 8
%N 5
%@ 2059-8688
%C London
%I BMJ
%M DZNE-2023-00487
%P 379-386
%D 2023
%X Retinal pathologies are an independent risk factor for ischaemic stroke, but research on the predictive value of retinal abnormalities for recurrent vascular events in patients with prior stroke is inconclusive. We investigated the association of retinal pathologies with subsequent vascular events.In a substudy of the Intensified secondary prevention intending a reduction of recurrent events in TIA and minor stroke patients (INSPiRE-TMS) trial, we enrolled patients with recent transient ischaemic attack (TIA) or minor stroke with at least one modifiable risk factor. Primary outcome was the composite of subsequent vascular events. Retinal photographs were taken at baseline and categorised into three different fundus groups by a telemedically linked ophthalmologist.722 patients participated in the current study and 109 major vascular events occurred. After multivariable adjustments, we did not find a significant association between fundus categories and risk for subsequent vascular events (HRs for moderate vascular retinopathy and vascular retinopathy with vessel rarefaction in comparison to no vascular retinopathy 1.03 (95
%K Humans
%K Stroke: diagnosis
%K Stroke: epidemiology
%K Stroke: complications
%K Ischemic Attack, Transient: diagnosis
%K Brain Ischemia
%K Hypertension: complications
%K Retinal Diseases: diagnosis
%K Retinal Diseases: epidemiology
%K Retinal Diseases: complications
%K Diabetes Mellitus
%K cerebral infarction (Other)
%K ischemic attack, transient (Other)
%K stroke (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%2 pmc:PMC10647888
%$ pmid:36858463
%R 10.1136/svn-2022-001784
%U https://pub.dzne.de/record/257690