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@ARTICLE{Toda:257693,
      author       = {Toda, Tomohisa and Parylak, Sarah L and Linker, Sara B and
                      Gage, Fred H},
      title        = {{T}he role of adult hippocampal neurogenesis in brain
                      health and disease.},
      journal      = {Molecular psychiatry},
      volume       = {24},
      number       = {1},
      issn         = {1359-4184},
      address      = {London},
      publisher    = {Macmillan},
      reportid     = {DZNE-2023-00490},
      pages        = {67 - 87},
      year         = {2019},
      abstract     = {Adult neurogenesis in the dentate gyrus of the hippocampus
                      is highly regulated by a number of environmental and
                      cell-intrinsic factors to adapt to environmental changes.
                      Accumulating evidence suggests that adult-born neurons may
                      play distinct physiological roles in hippocampus-dependent
                      functions, such as memory encoding and mood regulation. In
                      addition, several brain diseases, such as neurological
                      diseases and mood disorders, have deleterious effects on
                      adult hippocampal neurogenesis, and some symptoms of those
                      diseases can be partially explained by the dysregulation of
                      adult hippocampal neurogenesis. Here we review a possible
                      link between the physiological functions of adult-born
                      neurons and their roles in pathological conditions.},
      subtyp        = {Review Article},
      keywords     = {Adult / Affect: physiology / Brain: pathology / Brain:
                      physiology / Brain Diseases: pathology / Dentate Gyrus:
                      pathology / Dentate Gyrus: physiology / Hippocampus:
                      metabolism / Hippocampus: pathology / Hippocampus:
                      physiology / Humans / Memory: physiology / Neurogenesis:
                      physiology / Neuronal Plasticity: physiology / Neurons:
                      physiology / Temporal Lobe: pathology},
      ddc          = {610},
      pnm          = {899 - ohne Topic (POF4-899)},
      pid          = {G:(DE-HGF)POF4-899},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:29679070},
      pmc          = {pmc:PMC6195869},
      doi          = {10.1038/s41380-018-0036-2},
      url          = {https://pub.dzne.de/record/257693},
}