TY  - JOUR
AU  - Sabir, Hemmen
AU  - Maes, Elke
AU  - Zweyer, Margit
AU  - Schleehuber, Yvonne
AU  - Imam, Farhad B
AU  - Silverman, Jared
AU  - White, Yasmine
AU  - Pang, Raymand
AU  - Pasca, Anca M
AU  - Robertson, Nicola J
AU  - Maltepe, Emin
AU  - Bernis, Maria Eugenia
TI  - Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia-ischemia in newborn rats: a multi-drug randomized controlled screening trial.
JO  - Scientific reports
VL  - 13
IS  - 1
SN  - 2045-2322
CY  - [London]
PB  - Macmillan Publishers Limited, part of Springer Nature
M1  - DZNE-2023-00586
SP  - 9467
PY  - 2023
AB  - Intrapartum hypoxia-ischemia leading to neonatal encephalopathy (NE) results in significant neonatal mortality and morbidity worldwide, with > 85
KW  - Humans
KW  - Infant, Newborn
KW  - Animals
KW  - Rats
KW  - Neuroprotective Agents: pharmacology
KW  - Neuroprotective Agents: therapeutic use
KW  - Animals, Newborn
KW  - Allopurinol: pharmacology
KW  - Melatonin: pharmacology
KW  - Melatonin: therapeutic use
KW  - Caffeine: pharmacology
KW  - Clemastine: pharmacology
KW  - Hedgehog Proteins
KW  - Brain Injuries: drug therapy
KW  - Brain
KW  - Hypothermia, Induced: methods
KW  - Hypoxia-Ischemia, Brain: drug therapy
KW  - Hypoxia: drug therapy
KW  - Hydroxybutyrates: pharmacology
KW  - Asphyxia Neonatorum: drug therapy
KW  - Disease Models, Animal
KW  - Ischemia: therapy
KW  - Neuroprotective Agents (NLM Chemicals)
KW  - Allopurinol (NLM Chemicals)
KW  - Melatonin (NLM Chemicals)
KW  - Caffeine (NLM Chemicals)
KW  - Clemastine (NLM Chemicals)
KW  - Hedgehog Proteins (NLM Chemicals)
KW  - Hydroxybutyrates (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:37301929
C2  - pmc:PMC10257179
DO  - DOI:10.1038/s41598-023-36653-9
UR  - https://pub.dzne.de/record/258240
ER  -