%0 Journal Article
%A Riemenschneider, Henrick
%A Simonetti, Francesca
%A Sheth, Udit
%A Katona, Eszter
%A Roth, Stefan
%A Hutten, Saskia
%A Farny, Daniel
%A Michaelsen, Meike
%A Nuscher, Brigitte
%A Schmidt, Michael K
%A Flatley, Andrew
%A Schepers, Aloys
%A Gruijs da Silva, Lara A
%A Zhou, Qihui
%A Klopstock, Thomas
%A Liesz, Arthur
%A Arzberger, Thomas
%A Herms, Jochen
%A Feederle, Regina
%A Gendron, Tania F
%A Dormann, Dorothee
%A Edbauer, Dieter
%T Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
%J Acta Neuropathologica Communications
%V 11
%N 1
%@ 2051-5960
%C London
%I Biomed Central
%M DZNE-2023-00715
%P 112
%D 2023
%X Cytoplasmic aggregation and concomitant nuclear clearance of the RNA-binding protein TDP-43 are found in   90
%K Animals
%K Mice
%K Antibodies, Monoclonal
%K Epitopes
%K Immunization
%K Intermediate Filaments
%K NF-kappa B
%K Antibodies, Monoclonal (NLM Chemicals)
%K Aggregation (Other)
%K Amyotrophic lateral sclerosis (Other)
%K Frontotemporal dementia (Other)
%K Immunotherapy (Other)
%K Neurodegeneration (Other)
%K Phase separation (Other)
%K TDP-43 (Other)
%K Epitopes (NLM Chemicals)
%K NF-kappa B (NLM Chemicals)
%K TDP-43 protein, mouse (NLM Chemicals)
%F PUB:(DE-HGF)16
%9 Journal Article
%2 pmc:PMC10334564
%$ pmid:37434215
%R 10.1186/s40478-023-01592-z
%U https://pub.dzne.de/record/259006