TY  - JOUR
AU  - Riemenschneider, Henrick
AU  - Simonetti, Francesca
AU  - Sheth, Udit
AU  - Katona, Eszter
AU  - Roth, Stefan
AU  - Hutten, Saskia
AU  - Farny, Daniel
AU  - Michaelsen, Meike
AU  - Nuscher, Brigitte
AU  - Schmidt, Michael K
AU  - Flatley, Andrew
AU  - Schepers, Aloys
AU  - Gruijs da Silva, Lara A
AU  - Zhou, Qihui
AU  - Klopstock, Thomas
AU  - Liesz, Arthur
AU  - Arzberger, Thomas
AU  - Herms, Jochen
AU  - Feederle, Regina
AU  - Gendron, Tania F
AU  - Dormann, Dorothee
AU  - Edbauer, Dieter
TI  - Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
JO  - Acta Neuropathologica Communications
VL  - 11
IS  - 1
SN  - 2051-5960
CY  - London
PB  - Biomed Central
M1  - DZNE-2023-00715
SP  - 112
PY  - 2023
AB  - Cytoplasmic aggregation and concomitant nuclear clearance of the RNA-binding protein TDP-43 are found in   90
KW  - Animals
KW  - Mice
KW  - Antibodies, Monoclonal
KW  - Epitopes
KW  - Immunization
KW  - Intermediate Filaments
KW  - NF-kappa B
KW  - Antibodies, Monoclonal (NLM Chemicals)
KW  - Aggregation (Other)
KW  - Amyotrophic lateral sclerosis (Other)
KW  - Frontotemporal dementia (Other)
KW  - Immunotherapy (Other)
KW  - Neurodegeneration (Other)
KW  - Phase separation (Other)
KW  - TDP-43 (Other)
KW  - Epitopes (NLM Chemicals)
KW  - NF-kappa B (NLM Chemicals)
KW  - TDP-43 protein, mouse (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C2  - pmc:PMC10334564
C6  - pmid:37434215
DO  - DOI:10.1186/s40478-023-01592-z
UR  - https://pub.dzne.de/record/259006
ER  -