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000263549 041__ $$aEnglish
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000263549 1001_ $$aBabiloni, Claudio$$b0
000263549 245__ $$aRelationship between default mode network and resting-state electroencephalographic alpha rhythms in cognitively unimpaired seniors and patients with dementia due to Alzheimer’s disease
000263549 260__ $$aOxford$$bOxford Univ. Press$$c2023
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000263549 520__ $$a Here we tested the hypothesis of a relationship between the cortical default mode network (DMN) structural integrity and the resting-state electroencephalographic (rsEEG) rhythms in patients with Alzheimer's disease with dementia (ADD). Clinical and instrumental datasets in 45 ADD patients and 40 normal elderly (Nold) persons originated from the PDWAVES Consortium (www.pdwaves.eu). Individual rsEEG delta, theta, alpha, and fixed beta and gamma bands were considered. Freeware platforms served to derive (1) the (gray matter) volume of the DMN, dorsal attention (DAN), and sensorimotor (SMN) cortical networks and (2) the rsEEG cortical eLORETA source activities. We found a significant positive association between the DMN gray matter volume, the rsEEG alpha source activity estimated in the posterior DMN nodes (parietal and posterior cingulate cortex), and the global cognitive status in the Nold and ADD participants. Compared with the Nold, the ADD group showed lower DMN gray matter, lower rsEEG alpha source activity in those nodes, and lower global cognitive status. This effect was not observed in the DAN and SMN. These results suggest that the DMN structural integrity and the rsEEG alpha source activities in the DMN posterior hubs may be related and predict the global cognitive status in ADD and Nold persons.
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000263549 650_7 $$2Other$$aAlzheimer’s disease with dementia (ADD)
000263549 650_7 $$2Other$$aAlzheimer’s disease with dementia (ADD)
000263549 650_7 $$2Other$$aAlzheimer’s disease with dementia (ADD)
000263549 650_7 $$2Other$$aAlzheimer’s disease with dementia (ADD)
000263549 650_7 $$2Other$$aDefault mode network (DMN)
000263549 650_7 $$2Other$$aExact low-resolution brain electromagnetic source tomography (eLORETA)
000263549 650_7 $$2Other$$aResting state electroencephalographic (rsEEG) alpha rhythms
000263549 650_7 $$2Other$$aStructural magnetic resonance imaging (sMRI)
000263549 7001_ $$aLopez, Susanna$$b1
000263549 7001_ $$aNoce, Giuseppe$$b2
000263549 7001_ $$aFerri, Raffaele$$b3
000263549 7001_ $$aPanerai, Simonetta$$b4
000263549 7001_ $$aCatania, Valentina$$b5
000263549 7001_ $$aSoricelli, Andrea$$b6
000263549 7001_ $$aSalvatore, Marco$$b7
000263549 7001_ $$aNobili, Flavio$$b8
000263549 7001_ $$aArnaldi, Dario$$b9
000263549 7001_ $$aFamà, Francesco$$b10
000263549 7001_ $$aMassa, Federico$$b11
000263549 7001_ $$aButtinelli, Carla$$b12
000263549 7001_ $$aGiubilei, Franco$$b13
000263549 7001_ $$aStocchi, Fabrizio$$b14
000263549 7001_ $$aVacca, Laura$$b15
000263549 7001_ $$aMarizzoni, Moira$$b16
000263549 7001_ $$aD'Antonio, Fabrizia$$b17
000263549 7001_ $$aBruno, Giuseppe$$b18
000263549 7001_ $$aDe Lena, Carlo$$b19
000263549 7001_ $$aGüntekin, Bahar$$b20
000263549 7001_ $$00000-0002-7715-3035$$aYıldırım, Ebru$$b21
000263549 7001_ $$aHanoğlu, Lutfu$$b22
000263549 7001_ $$aYener, Görsev$$b23
000263549 7001_ $$aYerlikaya, Deniz$$b24
000263549 7001_ $$aTaylor, John Paul$$b25
000263549 7001_ $$0P:(DE-2719)9002248$$aSchumacher, Julia$$b26$$udzne
000263549 7001_ $$aMcKeith, Ian$$b27
000263549 7001_ $$aBonanni, Laura$$b28
000263549 7001_ $$aPantano, Patrizia$$b29
000263549 7001_ $$aPiervincenzi, Claudia$$b30
000263549 7001_ $$aPetsas, Nikolaos$$b31
000263549 7001_ $$aFrisoni, Giovanni B$$b32
000263549 7001_ $$aDel Percio, Claudio$$b33
000263549 7001_ $$aCarducci, Filippo$$b34
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