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@ARTICLE{Babiloni:263549,
author = {Babiloni, Claudio and Lopez, Susanna and Noce, Giuseppe and
Ferri, Raffaele and Panerai, Simonetta and Catania,
Valentina and Soricelli, Andrea and Salvatore, Marco and
Nobili, Flavio and Arnaldi, Dario and Famà, Francesco and
Massa, Federico and Buttinelli, Carla and Giubilei, Franco
and Stocchi, Fabrizio and Vacca, Laura and Marizzoni, Moira
and D'Antonio, Fabrizia and Bruno, Giuseppe and De Lena,
Carlo and Güntekin, Bahar and Yıldırım, Ebru and
Hanoğlu, Lutfu and Yener, Görsev and Yerlikaya, Deniz and
Taylor, John Paul and Schumacher, Julia and McKeith, Ian and
Bonanni, Laura and Pantano, Patrizia and Piervincenzi,
Claudia and Petsas, Nikolaos and Frisoni, Giovanni B and Del
Percio, Claudio and Carducci, Filippo},
title = {{R}elationship between default mode network and
resting-state electroencephalographic alpha rhythms in
cognitively unimpaired seniors and patients with dementia
due to {A}lzheimer’s disease},
journal = {Cerebral cortex},
volume = {33},
number = {20},
issn = {1047-3211},
address = {Oxford},
publisher = {Oxford Univ. Press},
reportid = {DZNE-2023-00825},
pages = {10514 - 10527},
year = {2023},
abstract = {Here we tested the hypothesis of a relationship between the
cortical default mode network (DMN) structural integrity and
the resting-state electroencephalographic (rsEEG) rhythms in
patients with Alzheimer's disease with dementia (ADD).
Clinical and instrumental datasets in 45 ADD patients and 40
normal elderly (Nold) persons originated from the PDWAVES
Consortium (www.pdwaves.eu). Individual rsEEG delta, theta,
alpha, and fixed beta and gamma bands were considered.
Freeware platforms served to derive (1) the (gray matter)
volume of the DMN, dorsal attention (DAN), and sensorimotor
(SMN) cortical networks and (2) the rsEEG cortical eLORETA
source activities. We found a significant positive
association between the DMN gray matter volume, the rsEEG
alpha source activity estimated in the posterior DMN nodes
(parietal and posterior cingulate cortex), and the global
cognitive status in the Nold and ADD participants. Compared
with the Nold, the ADD group showed lower DMN gray matter,
lower rsEEG alpha source activity in those nodes, and lower
global cognitive status. This effect was not observed in the
DAN and SMN. These results suggest that the DMN structural
integrity and the rsEEG alpha source activities in the DMN
posterior hubs may be related and predict the global
cognitive status in ADD and Nold persons.},
keywords = {Alzheimer’s disease with dementia (ADD) (Other) /
Alzheimer’s disease with dementia (ADD) (Other) /
Alzheimer’s disease with dementia (ADD) (Other) /
Alzheimer’s disease with dementia (ADD) (Other) / Default
mode network (DMN) (Other) / Exact low-resolution brain
electromagnetic source tomography (eLORETA) (Other) /
Resting state electroencephalographic (rsEEG) alpha rhythms
(Other) / Structural magnetic resonance imaging (sMRI)
(Other)},
cin = {AG Storch},
ddc = {610},
cid = {I:(DE-2719)5000014},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:37615301},
pmc = {pmc:PMC10588004},
doi = {10.1093/cercor/bhad300},
url = {https://pub.dzne.de/record/263549},
}