% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@INBOOK{Scholz:263611,
      author       = {Scholz, Rebekka and Brösamle, Desirée and Yuan, Xidi and
                      Neher, Jonas J and Beyer, Marc},
      title        = {{C}ombined {A}nalysis of m{RNA} {E}xpression and {O}pen
                      {C}hromatin in {M}icroglia.},
      volume       = {2713},
      address      = {New York, NY},
      publisher    = {Springer US},
      reportid     = {DZNE-2023-00833},
      isbn         = {978-1-0716-3436-3 (print)},
      series       = {Methods in Molecular Biology},
      pages        = {543 - 571},
      year         = {2024},
      comment      = {Tissue-Resident Macrophages / Mass, Elvira (Editor) ; New
                      York, NY : Springer US, 2024, Chapter 35 ; ISSN:
                      1064-3745=1940-6029 ; ISBN:
                      978-1-0716-3436-3=978-1-0716-3437-0 ;
                      doi:10.1007/978-1-0716-3437-0},
      booktitle     = {Tissue-Resident Macrophages / Mass,
                       Elvira (Editor) ; New York, NY :
                       Springer US, 2024, Chapter 35 ; ISSN:
                       1064-3745=1940-6029 ; ISBN:
                       978-1-0716-3436-3=978-1-0716-3437-0 ;
                       doi:10.1007/978-1-0716-3437-0},
      abstract     = {The advance of single-cell RNA-sequencing technologies in
                      the past years has enabled unprecedented insights into the
                      complexity and heterogeneity of microglial cell states in
                      the homeostatic and diseased brain. This includes rather
                      complex proteomic, metabolomic, morphological,
                      transcriptomic, and epigenetic adaptations to external
                      stimuli and challenges resulting in a novel concept of core
                      microglia properties and functions. To uncover the
                      regulatory programs facilitating the rapid transcriptomic
                      adaptation in response to changes in the local
                      microenvironment, the accessibility of gene bodies and gene
                      regulatory elements can be assessed. Here, we describe the
                      application of a previously published method for
                      simultaneous high-throughput ATAC and RNA expression with
                      sequencing (SHARE-seq) on microglia nuclei isolated from
                      frozen mouse brain tissue.},
      keywords     = {Animals / Mice / Chromatin: genetics / Microglia /
                      Proteomics / RNA, Messenger: genetics / RNA / Bioinformatics
                      (Other) / Chromatin accessibility (Other) / Epigenetics
                      (Other) / Microglia (Other) / Multiomics (Other) /
                      Single-nucleus sequencing (Other) / Transcriptomics (Other)
                      / Chromatin (NLM Chemicals) / RNA, Messenger (NLM Chemicals)
                      / RNA (NLM Chemicals)},
      cin          = {AG Beyer / AG Neher (Tübingen) / PRECISE},
      ddc          = {570},
      cid          = {I:(DE-2719)1013035 / I:(DE-2719)1210012 /
                      I:(DE-2719)1013031},
      pnm          = {351 - Brain Function (POF4-351) / 352 - Disease Mechanisms
                      (POF4-352)},
      pid          = {G:(DE-HGF)POF4-351 / G:(DE-HGF)POF4-352},
      experiment   = {EXP:(DE-2719)PRECISE-20190321},
      typ          = {PUB:(DE-HGF)7},
      pubmed       = {pmid:37639146},
      doi          = {10.1007/978-1-0716-3437-0_35},
      url          = {https://pub.dzne.de/record/263611},
}