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@ARTICLE{Rauchmann:265665,
      author       = {Rauchmann, Boris-Stephan and Gross, Patrizia and Ersoezlue,
                      Ersin and Wagner, Michael and Ballarini, Tommaso and Kurz,
                      Carolin and Tatò, Maia and Utecht, Julia and Papazov, Boris
                      and Guersel, Selim and Totzke, Marie and Trappmann, Lena and
                      Burow, Lena and Koller, Gabriele and Stöcklein, Sophia and
                      Keeser, Daniel and Altenstein, Slawek and Bartels, Claudia
                      and Buerger, Katharina and Dechent, Peter and Dobisch, Laura
                      and Ewers, Michael and Fliessbach, Klaus and Freiesleben,
                      Silka Dawn and Glanz, Wenzel and Görß, Doreen and Gref,
                      Daria and Haynes, John Dylan and Janowitz, Daniel and
                      Kilimann, Ingo and Kimmich, Okka and Kleineidam, Luca and
                      Laske, Christoph and Lohse, Andrea and Maier, Franziska and
                      Metzger, Coraline D. and Munk, Matthias H. and Peters,
                      Oliver and Preis, Lukas and Priller, Josef and Roeske,
                      Sandra and Roy, Nina and Sanzenbacher, Carolin and
                      Scheffler, Klaus and Schneider, Anja and Schott, Björn
                      Hendrik and Spottke, Annika and Spruth, Eike Jakob and
                      Teipel, Stefan and van Lent, Debora Melo and Wiltfang, Jens
                      and Wolfsgruber, Steffen and Yakupov, Renat and Düzel,
                      Emrah and Jessen, Frank and Perneczky, Robert},
      title        = {{A} 6-items {Q}uestionnaire (6-{QMD}) captures a
                      {M}editerranean like dietary pattern and is associated with
                      memory performance and hippocampal volume in elderly and
                      persons at risk for {A}lzheimer’s disease},
      journal      = {Nutrition and healthy aging},
      volume       = {8},
      number       = {1},
      issn         = {2451-9480},
      address      = {Amsterdam},
      publisher    = {IOS Press},
      reportid     = {DZNE-2023-01014},
      pages        = {143 - 156},
      year         = {2023},
      abstract     = {There is evidence that adherence to Mediterranean-like diet
                      reduces cognitive decline and brain atrophy in Alzheimer's
                      disease (AD). However, lengthy dietary assessments, such as
                      food frequency questionnaires (FFQs), discourage more
                      frequent use.OBJECTIVE:Here we aimed to validate a 6-items
                      short questionnaire for a Mediterranean-like diet (6-QMD)
                      and explore its associations with memory performance and
                      hippocampal atrophy in healthy elders and individuals at
                      risk for AD.METHODS:We analyzed 938 participants (N = 234
                      healthy controls and N = 704 participants with an increased
                      AD risk) from the DZNE-Longitudinal Cognitive Impairment and
                      Dementia Study (DELCODE). The 6-QMD was validated against
                      the Mediterranean Diet (MeDi) score and the
                      Mediterranean-DASH Diet Intervention for Neurodegenerative
                      Delay (MIND) score, both derived from a detailed FFQ.
                      Furthermore, associations between the 6-QMD and memory
                      function as well as hippocampal atrophy were evaluated using
                      linear regressions.RESULTS:The 6-QMD was moderately
                      associated with the FFQ-derived MeDi adherence score (ρ =
                      0.25, p < 0.001) and the MIND score (ρ = 0.37, p= < 0.001).
                      Higher fish and olive oil consumption and lower meat and
                      sausage consumption showed significant associations in a
                      linear regression, adjusted for diagnosis, age, sex and
                      education, with memory function (β = 0.1, p = 0.008) and
                      bilateral hippocampal volumes (left: β = 0.15, p < 0.001);
                      (right: β = 0.18, p < 0.001)).CONCLUSIONS:The 6-QMD is a
                      useful and valid brief tool to assess the adherence to MeDi
                      and MIND diets, capturing associations with memory function
                      and brain atrophy in healthy elders and individuals at
                      increased AD dementia risk, making it a valid alternative in
                      settings with time constraints.},
      cin          = {AG Dichgans / AG Simons / AG Düzel / AG Wagner / AG Endres
                      / Clinical Research (Munich) / Patient Studies Bonn / AG
                      Jessen / AG Teipel / AG Gasser / Core Technical Staff / Core
                      ICRU / AG Wiltfang / AG Spottke / AG Priller / AG Peters /
                      AG Schneider / AG Fischer},
      ddc          = {630},
      cid          = {I:(DE-2719)5000022 / I:(DE-2719)1110008 /
                      I:(DE-2719)5000006 / I:(DE-2719)1011201 / I:(DE-2719)1811005
                      / I:(DE-2719)1111015 / I:(DE-2719)1011101 /
                      I:(DE-2719)1011102 / I:(DE-2719)1510100 / I:(DE-2719)1210000
                      / I:(DE-2719)1340007 / I:(DE-2719)1240005 /
                      I:(DE-2719)1410006 / I:(DE-2719)1011103 / I:(DE-2719)5000007
                      / I:(DE-2719)5000000 / I:(DE-2719)1011305 /
                      I:(DE-2719)1410002},
      pnm          = {353 - Clinical and Health Care Research (POF4-353) / 352 -
                      Disease Mechanisms (POF4-352) / 351 - Brain Function
                      (POF4-351)},
      pid          = {G:(DE-HGF)POF4-353 / G:(DE-HGF)POF4-352 /
                      G:(DE-HGF)POF4-351},
      experiment   = {EXP:(DE-2719)DELCODE-20140101},
      typ          = {PUB:(DE-HGF)16},
      doi          = {10.3233/NHA-220190},
      url          = {https://pub.dzne.de/record/265665},
}