TY  - JOUR
AU  - Shrouder, Joshua James
AU  - Calandra, Gian-Marco
AU  - Filser, Severin
AU  - Varga, Daniel Peter
AU  - Besson-Girard, Simon
AU  - Mamrak, Uta
AU  - Dorok, Maximilian
AU  - Bulut-Impraim, Buket
AU  - Seker, Fatma Burcu
AU  - Gesierich, Benno
AU  - Laredo, Fabio
AU  - Wehn, Antonia Clarissa
AU  - Khalin, Igor
AU  - Bayer, Patrick
AU  - Liesz, Arthur
AU  - Gökce, Ozgun
AU  - Plesnila, Nikolaus
TI  - Continued dysfunction of capillary pericytes promotes no-reflow after experimental stroke in vivo.
JO  - Brain
VL  - 147
IS  - 3
SN  - 0006-8950
CY  - Oxford
PB  - Oxford Univ. Press
M1  - DZNE-2024-00246
SP  - 1057 - 1074
PY  - 2024
AB  - Incomplete reperfusion of the microvasculature ('no-reflow') after ischaemic stroke damages salvageable brain tissue. Previous ex vivo studies suggest pericytes are vulnerable to ischaemia and may exacerbate no-reflow, but the viability of pericytes and their association with no-reflow remains under-explored in vivo. Using longitudinal in vivo two-photon single-cell imaging over 7 days, we showed that 87
KW  - Humans
KW  - Stroke
KW  - Pericytes: physiology
KW  - Brain Ischemia
KW  - Ischemic Stroke
KW  - Cerebral Infarction
KW  - cerebral ischaemia (Other)
KW  - ischaemic stroke (Other)
KW  - no-reflow (Other)
KW  - pericytes (Other)
KW  - reperfusion (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:38153327
DO  - DOI:10.1093/brain/awad401
UR  - https://pub.dzne.de/record/268500
ER  -