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@ARTICLE{Flynn:268859,
      author       = {Flynn, Kevin},
      title        = {{T}he cytoskeleton and neurite initiation.},
      journal      = {BioArchitecture},
      volume       = {3},
      number       = {4},
      issn         = {1949-0992},
      address      = {Austin, Tex.},
      publisher    = {Landes Bioscience},
      reportid     = {DZNE-2024-00358},
      pages        = {86 - 109},
      year         = {2013},
      abstract     = {Neurons begin their life as simple spheres, but can
                      ultimately assume an elaborate morphology with numerous,
                      highly arborized dendrites, and long axons. This is achieved
                      via an astounding developmental progression which is
                      dependent upon regulated assembly and dynamics of the
                      cellular cytoskeleton. As neurites emerge out of the soma,
                      neurons break their spherical symmetry and begin to acquire
                      the morphological features that define their structure and
                      function. Neurons regulate their cytoskeleton to achieve
                      changes in cell shape, velocity, and direction as they
                      migrate, extend neurites, and polarize. Of particular
                      importance, the organization and dynamics of actin and
                      microtubules directs the migration and morphogenesis of
                      neurons. This review focuses on the regulation of intrinsic
                      properties of the actin and microtubule cytoskeletons and
                      how specific cytoskeletal structures and dynamics are
                      associated with the earliest phase of neuronal
                      morphogenesis—neuritogenesis.},
      subtyp        = {Review Article},
      keywords     = {Actins: metabolism / Animals / Cytoskeleton: metabolism /
                      Humans / Morphogenesis / Neurites: metabolism / Neurons:
                      cytology / Neurons: metabolism / Actins (NLM Chemicals)},
      cin          = {AG Bradke},
      ddc          = {570},
      cid          = {I:(DE-2719)1013002},
      pnm          = {351 - Brain Function (POF4-351)},
      pid          = {G:(DE-HGF)POF4-351},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:24002528},
      pmc          = {pmc:PMC4201609},
      doi          = {10.4161/bioa.26259},
      url          = {https://pub.dzne.de/record/268859},
}