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000268872 1001_ $$aLenzoni, S.$$b0
000268872 245__ $$aNeurochemistry of executive functions
000268872 260__ $$bElsevier$$c2025
000268872 29510 $$aEncyclopedia of the Human Brain / Lenzoni, S. ; : Elsevier, 2025, ; ISBN: 9780128204818 ; doi:10.1016/B978-0-12-820480-1.00065-6
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000268872 520__ $$aNeurochemical modulation of executive functions in the human brain is complex. While a lot still remains unknown, also concerning interactions and collaborations among neurochemical modulators as well as population-specific optimal dose-response relationships, some initial insights on the neurochemistry of executive functions exist. Fronto-striatal as well as hippocampal levels of dopamine are modulating working memory, cognitive flexibility and inhibition. Noradrenaline and acetylcholine support the regulation of attention via action on frontal as well as sensory areas. Higher prefrontal levels of serotonin are detrimental for working memory and inhibition. Higher prefrontal levels of glutamate and GABA benefit working memory and response inhibition, respectively.
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000268872 7001_ $$0P:(DE-2719)9002076$$aGuruprasath, G.$$b1$$udzne
000268872 7001_ $$aZhunussova, A.$$b2
000268872 7001_ $$0P:(DE-2719)9001927$$aLeiman, M.$$b3$$udzne
000268872 7001_ $$0P:(DE-2719)9002575$$aLudwig, M.$$b4$$udzne
000268872 7001_ $$0P:(DE-2719)9002723$$aPenalba Sánchez, L.$$b5$$udzne
000268872 7001_ $$0P:(DE-2719)2811927$$aHämmerer, D.$$b6$$eLast author$$udzne
000268872 773__ $$a10.1016/B978-0-12-820480-1.00065-6
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