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@INBOOK{Lenzoni:268872,
      author       = {Lenzoni, S. and Guruprasath, G. and Zhunussova, A. and
                      Leiman, M. and Ludwig, M. and Penalba Sánchez, L. and
                      Hämmerer, D.},
      title        = {{N}eurochemistry of executive functions},
      publisher    = {Elsevier},
      reportid     = {DZNE-2024-00371},
      pages        = {57 - 80},
      year         = {2025},
      comment      = {Encyclopedia of the Human Brain / Lenzoni, S. ; : Elsevier,
                      2025, ; ISBN: 9780128204818 ;
                      doi:10.1016/B978-0-12-820480-1.00065-6},
      booktitle     = {Encyclopedia of the Human Brain /
                       Lenzoni, S. ; : Elsevier, 2025, ; ISBN:
                       9780128204818 ;
                       doi:10.1016/B978-0-12-820480-1.00065-6},
      abstract     = {Neurochemical modulation of executive functions in the
                      human brain is complex. While a lot still remains unknown,
                      also concerning interactions and collaborations among
                      neurochemical modulators as well as population-specific
                      optimal dose-response relationships, some initial insights
                      on the neurochemistry of executive functions exist.
                      Fronto-striatal as well as hippocampal levels of dopamine
                      are modulating working memory, cognitive flexibility and
                      inhibition. Noradrenaline and acetylcholine support the
                      regulation of attention via action on frontal as well as
                      sensory areas. Higher prefrontal levels of serotonin are
                      detrimental for working memory and inhibition. Higher
                      prefrontal levels of glutamate and GABA benefit working
                      memory and response inhibition, respectively.},
      cin          = {AG Düzel / AG Müller},
      cid          = {I:(DE-2719)5000006 / I:(DE-2719)1310003},
      pnm          = {353 - Clinical and Health Care Research (POF4-353)},
      pid          = {G:(DE-HGF)POF4-353},
      typ          = {PUB:(DE-HGF)7},
      doi          = {10.1016/B978-0-12-820480-1.00065-6},
      url          = {https://pub.dzne.de/record/268872},
}