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@INPROCEEDINGS{Campbell:268890,
author = {Campbell, Alexander and Spasov, Simeon and Toschi, Nicola
and Lio, Pietro},
title = {{DBGDGM}: {D}ynamic {B}rain {G}raph {D}eep {G}enerative
{M}odel},
volume = {227},
reportid = {DZNE-2024-00389},
pages = {1346-1371},
year = {2024},
note = {ISSN 2640-3498: Proceedings of Machine Learning Research},
abstract = {Graphs are a natural representation of brain activity
derived from functional magnetic imaging (fMRI) data. It is
well known that clusters of anatomical brain regions, known
as functional connectivity networks (FCNs), encode temporal
relationships which can serve as useful biomarkers for
understanding brain function and dysfunction. Previous
works, however, ignore the temporal dynamics of the brain
and focus on static graphs. In this paper, we propose a
dynamic brain graph deep generative model (DBGDGM) which
simultaneously clusters brain regions into temporally
evolving communities and learns dynamic unsupervised node
embeddings. Specifically, DBGDGM represents brain graph
nodes as embeddings sampled from a distribution over
communities that evolve over time. We parameterise this
community distribution using neural networks that learn from
subject and node embeddings as well as past community
assignments. Experiments demonstrate DBGDGM outperforms
baselines in graph generation, dynamic link prediction, and
is comparable for graph classification. Finally, an analysis
of the learnt community distributions reveals overlap with
known FCNs reported in neuroscience literature.},
month = {Jul},
date = {2023-07-10},
organization = {Medical Imaging with Deep Learning,
Nashville, Tenn. (USA), 10 Jul 2023 -
12 Jul 2023},
cin = {AG Mukherjee},
cid = {I:(DE-2719)1013030},
pnm = {354 - Disease Prevention and Healthy Aging (POF4-354)},
pid = {G:(DE-HGF)POF4-354},
typ = {PUB:(DE-HGF)8},
url = {https://pub.dzne.de/record/268890},
}