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001     269000
005     20260212164544.0
024 7 _ |2 doi
|a 10.1007/s12268-023-2066-9
024 7 _ |2 ISSN
|a 0947-0867
024 7 _ |2 ISSN
|a 1868-6249
037 _ _ |a DZNE-2024-00434
082 _ _ |a 540
100 1 _ |0 P:(DE-2719)2812244
|a Fengler, Sven
|b 0
|e First author
|u dzne
245 _ _ |a Künstliche Hirngefäße zur Identifikation hirngängiger Wirkstoffe
260 _ _ |a Heidelberg
|b Spektrum
|c 2023
336 7 _ |2 DRIVER
|a article
336 7 _ |2 DataCite
|a Output Types/Journal article
336 7 _ |0 PUB:(DE-HGF)16
|2 PUB:(DE-HGF)
|a Journal Article
|b journal
|m journal
|s 1713774412_6652
336 7 _ |2 BibTeX
|a ARTICLE
336 7 _ |2 ORCID
|a JOURNAL_ARTICLE
336 7 _ |0 0
|2 EndNote
|a Journal Article
520 _ _ |a Due to the regulatory function of the human blood-brain barrier (BBB), optimizing brain-targeting drugs for brain-penetration is a challenge in drug discovery. Therefore, the development of in vitro assays that mimic relevant properties of the BBB are in focus to better predict drug permeability in humans. This article describes human iPSC-derived brain endothelial microvessels in perfusable multi-chip plates that provide physiological properties of the BBB in a scalable format for screening.
536 _ _ |0 G:(DE-HGF)POF4-899
|a 899 - ohne Topic (POF4-899)
|c POF4-899
|f POF IV
|x 0
588 _ _ |a Dataset connected to CrossRef, Journals: pub.dzne.de
693 _ _ |0 EXP:(DE-2719)LAT-20190308
|5 EXP:(DE-2719)LAT-20190308
|e Laboratory Automation Technologies (CRFS-LAT) / Bonn
|x 0
700 1 _ |0 P:(DE-2719)2810323
|a Kurkowsky, Birgit
|b 1
|u dzne
700 1 _ |a Heimlich, Gerd
|b 2
700 1 _ |0 P:(DE-2719)2159508
|a Fava, Eugenio
|b 3
|u dzne
700 1 _ |0 P:(DE-2719)2810245
|a Denner, Philip
|b 4
|e Last author
|u dzne
773 _ _ |0 PERI:(DE-600)2203536-9
|a 10.1007/s12268-023-2066-9
|g Vol. 29, no. 7, p. 766 - 767
|n 7
|p 766 - 767
|t Biospektrum
|v 29
|x 0947-0867
|y 2023
856 4 _ |u https://pub.dzne.de/record/269000/files/DZNE-2024-00434.pdf
856 4 _ |u https://pub.dzne.de/record/269000/files/DZNE-2024-00434.pdf?subformat=pdfa
|x pdfa
909 C O |o oai:pub.dzne.de:269000
|p VDB
910 1 _ |0 I:(DE-588)1065079516
|6 P:(DE-2719)2812244
|a Deutsches Zentrum für Neurodegenerative Erkrankungen
|b 0
|k DZNE
910 1 _ |0 I:(DE-588)1065079516
|6 P:(DE-2719)2810323
|a Deutsches Zentrum für Neurodegenerative Erkrankungen
|b 1
|k DZNE
910 1 _ |0 I:(DE-588)1065079516
|6 P:(DE-2719)2159508
|a Deutsches Zentrum für Neurodegenerative Erkrankungen
|b 3
|k DZNE
910 1 _ |0 I:(DE-588)1065079516
|6 P:(DE-2719)2810245
|a Deutsches Zentrum für Neurodegenerative Erkrankungen
|b 4
|k DZNE
913 1 _ |0 G:(DE-HGF)POF4-899
|1 G:(DE-HGF)POF4-890
|2 G:(DE-HGF)POF4-800
|3 G:(DE-HGF)POF4
|4 G:(DE-HGF)POF
|a DE-HGF
|b Programmungebundene Forschung
|l ohne Programm
|v ohne Topic
|x 0
914 1 _ |y 2023
915 _ _ |0 StatID:(DE-HGF)3002
|2 StatID
|a DEAL Springer
|d 2023-08-22
|w ger
915 _ _ |0 StatID:(DE-HGF)3002
|2 StatID
|a DEAL Springer
|d 2023-08-22
|w ger
915 _ _ |0 StatID:(DE-HGF)0200
|2 StatID
|a DBCoverage
|b SCOPUS
|d 2023-08-22
915 _ _ |0 StatID:(DE-HGF)0300
|2 StatID
|a DBCoverage
|b Medline
|d 2023-08-22
920 1 _ |0 I:(DE-2719)1040190
|k LAT
|l Laboratory Automation Technologies (CRFS-LAT)
|x 0
920 1 _ |0 I:(DE-2719)1040000
|k AG Fava
|l Core Research Facilities & Services
|x 1
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a I:(DE-2719)1040190
980 _ _ |a I:(DE-2719)1040000
980 _ _ |a UNRESTRICTED

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