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@ARTICLE{Chan:270187,
      author       = {Chan, Chi Wai and Chen, Nannan and Hernandez, John and
                      Meltzer, Hagar and Park, Annie and Stahl, Aaron},
      title        = {{F}uture avenues in {D}rosophila mushroom body research.},
      journal      = {Learning $\&$ memory},
      volume       = {31},
      number       = {5},
      issn         = {1072-0502},
      address      = {Plainview, NY},
      publisher    = {Cold Spring Harbor Laboratory Press},
      reportid     = {DZNE-2024-00758},
      pages        = {a053863},
      year         = {2024},
      abstract     = {How does the brain translate sensory information into
                      complex behaviors? With relatively small neuronal numbers,
                      readable behavioral outputs, and an unparalleled genetic
                      toolkit, the Drosophila mushroom body (MB) offers an
                      excellent model to address this question in the context of
                      associative learning and memory. Recent technological
                      breakthroughs, such as the freshly completed full-brain
                      connectome, multiomics approaches, CRISPR-mediated gene
                      editing, and machine learning techniques, led to major
                      advancements in our understanding of the MB circuit at the
                      molecular, structural, physiological, and functional levels.
                      Despite significant progress in individual MB areas, the
                      field still faces the fundamental challenge of resolving how
                      these different levels combine and interact to ultimately
                      control the behavior of an individual fly. In this review,
                      we discuss various aspects of MB research, with a focus on
                      the current knowledge gaps, and an outlook on the future
                      methodological developments required to reach an overall
                      view of the neurobiological basis of learning and memory.},
      subtyp        = {Review Article},
      keywords     = {Mushroom Bodies: physiology / Animals / Drosophila:
                      physiology / Memory: physiology / Association Learning:
                      physiology},
      cin          = {AG Gründemann},
      ddc          = {150},
      cid          = {I:(DE-2719)5000069},
      pnm          = {351 - Brain Function (POF4-351)},
      pid          = {G:(DE-HGF)POF4-351},
      typ          = {PUB:(DE-HGF)16},
      pmc          = {pmc:PMC11199946},
      pubmed       = {pmid:38862172},
      doi          = {10.1101/lm.053863.123},
      url          = {https://pub.dzne.de/record/270187},
}