%0 Journal Article
%A Levin, Johannes
%A Baiardi, Simone
%A Quadalti, Corinne
%A Rossi, Marcello
%A Mammana, Angela
%A Vöglein, Jonathan
%A Bernhardt, Alexander
%A Perrin, Richard J
%A Jucker, Mathias
%A Preische, Oliver
%A Hofmann, Anna
%A Höglinger, Günter U
%A Cairns, Nigel J
%A Franklin, Erin E
%A Chrem, Patricio
%A Cruchaga, Carlos
%A Berman, Sarah B
%A Chhatwal, Jasmeer P
%A Daniels, Alisha
%A Day, Gregory S
%A Ryan, Natalie S
%A Goate, Alison M
%A Gordon, Brian A
%A Huey, Edward D
%A Ibanez, Laura
%A Karch, Celeste M
%A Lee, Jae-Hong
%A Llibre-Guerra, Jorge
%A Lopera, Francisco
%A Masters, Colin L
%A Morris, John C
%A Noble, James M
%A Renton, Alan E
%A Roh, Jee Hoon
%A Frosch, Matthew P
%A Keene, C Dirk
%A McLean, Catriona
%A Sanchez-Valle, Raquel
%A Schofield, Peter R
%A Supnet-Bell, Charlene
%A Xiong, Chengjie
%A Giese, Armin
%A Hansson, Oskar
%A Bateman, Randall J
%A McDade, Eric
%A Parchi, Piero
%T α-Synuclein seed amplification assay detects Lewy body co-pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden.
%J Alzheimer's and dementia
%V 20
%N 6
%@ 1552-5260
%C Hoboken, NJ
%I Wiley
%M DZNE-2024-00783
%P 4351 - 4365
%D 2024
%X Amyloid beta and tau pathology are the hallmarks of sporadic Alzheimer's disease (AD) and autosomal dominant AD (ADAD). However, Lewy body pathology (LBP) is found in ≈ 50
%K Alzheimer Disease: diagnosis
%K Humans
%K Alzheimer Disease: genetics
%K Alzheimer Disease: pathology
%K Alzheimer Disease: cerebrospinal fluid
%K alpha-Synuclein: cerebrospinal fluid
%K alpha-Synuclein: genetics
%K Female
%K Male
%K Middle Aged
%K Lewy Bodies: pathology
%K Aged
%K Mutation
%K Brain: pathology
%K Amyloid beta-Peptides: cerebrospinal fluid
%K Amyloid beta-Peptides: metabolism
%K Disease Progression
%K alpha‐synuclein seed amplification assay (Other)
%K Dominantly Inherited Alzheimer Network (Other)
%K Lewy body pathology (Other)
%K alpha‐synuclein seed amplification assay (Other)
%K real‐time quaking‐induced conversion (Other)
%K alpha-Synuclein (NLM Chemicals)
%K Amyloid beta-Peptides (NLM Chemicals)
%K real‐time quaking‐induced conversion (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38666355
%2 pmc:PMC11180868
%R 10.1002/alz.13818
%U https://pub.dzne.de/record/270311