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@ARTICLE{Mioni:270712,
author = {Mioni, Giovanna and Wolbers, Thomas and Riemer, Martin},
title = {{D}ifferences between sub-second and supra-second durations
for the assessment of timing deficits in amnestic mild
cognitive impairment},
journal = {Aging brain},
volume = {6},
issn = {2589-9589},
address = {Amsterdam},
publisher = {Elsevier},
reportid = {DZNE-2024-00884},
pages = {100120},
year = {2024},
abstract = {Previous studies have often reported timing deficits in
older adults with different degrees of cognitive decline,
however, the exact nature of impairments in time perception
is still to be elucidated. In particular, it is unclear if
the deficits are more pronounced for short or long
intervals, consistent with notions that different cognitive
processes and neuroanatomical areas are involved in the
processing of durations of different ranges. The present
study aims to further investigate timing abilities in
amnestic mild cognitive impairment (aMCI) patients and
age-matched controls. Participants were asked to decide
whether an acoustic event occurred within the first or the
second half of a reference duration. The results revealed a
bias towards larger PSE values and reduced precision in aMCI
patients compared to healthy controls. Further analyses
showed that the bias towards larger PSE values correlated
with memory performance, especially when sub-second
durations were tested. Overall, the results demonstrate that
memory deficits in aMCI patients coincide with changes in
time perception in the sub-second interval range.},
keywords = {Aging (Other) / Cognitive decline (Other) / Mild cognitive
impairment (Other) / Short-long temporal intervals (Other) /
Time perception (Other)},
cin = {AG Wolbers},
ddc = {610},
cid = {I:(DE-2719)1310002},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:39044775},
pmc = {pmc:PMC11261004},
doi = {10.1016/j.nbas.2024.100120},
url = {https://pub.dzne.de/record/270712},
}