%0 Journal Article
%A Riemann, Steffen
%A van Lück, Jil
%A Rodríguez-Fornells, Antoni
%A Flöel, Agnes
%A Meinzer, Marcus
%T The role of frontal cortex in novel-word learning and consolidation: Evidence from focal transcranial direct current stimulation.
%J Cortex
%V 177
%@ 0010-9452
%C New York, NY
%I Elsevier
%M DZNE-2024-00935
%P 15 - 27
%D 2024
%X Previous studies have demonstrated that conventional transcranial direct current stimulation (tDCS) can enhance novel-word learning. However, because of the widespread current that is induced by these setups and lack of appropriate control conditions, little is known about the underlying neural mechanisms. In the present double-blinded and sham-tDCS controlled study, we investigated for the first time if regionally precise focal tDCS targeting two key nodes of the novel-word learning network at different time points would result in regionally and temporally distinct effects. 156 participants completed a contextual novel-word-learning paradigm and learning success was probed immediately after the acquisition period and 30-min later. Participants were randomly assigned to six stimulation conditions: Active tDCS (1.5 mA) was administered to left inferior frontal (IFG) or middle temporal gyrus (MTG), either during acquisition or delayed recall. Control groups received sham-tDCS either during acquisition or delayed recall (50
%K Humans
%K Transcranial Direct Current Stimulation: methods
%K Male
%K Female
%K Adult
%K Frontal Lobe: physiology
%K Young Adult
%K Learning: physiology
%K Double-Blind Method
%K Mental Recall: physiology
%K Temporal Lobe: physiology
%K Memory Consolidation: physiology
%K Inferior frontal gyrus (Other)
%K Middle temporal gyrus (Other)
%K Novel word learning (Other)
%K Regional specificity (Other)
%K Temporal specificity (Other)
%K focal tDCS (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:38824804
%R 10.1016/j.cortex.2024.05.004
%U https://pub.dzne.de/record/271063