TY  - JOUR
AU  - Riemann, Steffen
AU  - van Lück, Jil
AU  - Rodríguez-Fornells, Antoni
AU  - Flöel, Agnes
AU  - Meinzer, Marcus
TI  - The role of frontal cortex in novel-word learning and consolidation: Evidence from focal transcranial direct current stimulation.
JO  - Cortex
VL  - 177
SN  - 0010-9452
CY  - New York, NY
PB  - Elsevier
M1  - DZNE-2024-00935
SP  - 15 - 27
PY  - 2024
AB  - Previous studies have demonstrated that conventional transcranial direct current stimulation (tDCS) can enhance novel-word learning. However, because of the widespread current that is induced by these setups and lack of appropriate control conditions, little is known about the underlying neural mechanisms. In the present double-blinded and sham-tDCS controlled study, we investigated for the first time if regionally precise focal tDCS targeting two key nodes of the novel-word learning network at different time points would result in regionally and temporally distinct effects. 156 participants completed a contextual novel-word-learning paradigm and learning success was probed immediately after the acquisition period and 30-min later. Participants were randomly assigned to six stimulation conditions: Active tDCS (1.5 mA) was administered to left inferior frontal (IFG) or middle temporal gyrus (MTG), either during acquisition or delayed recall. Control groups received sham-tDCS either during acquisition or delayed recall (50
KW  - Humans
KW  - Transcranial Direct Current Stimulation: methods
KW  - Male
KW  - Female
KW  - Adult
KW  - Frontal Lobe: physiology
KW  - Young Adult
KW  - Learning: physiology
KW  - Double-Blind Method
KW  - Mental Recall: physiology
KW  - Temporal Lobe: physiology
KW  - Memory Consolidation: physiology
KW  - Inferior frontal gyrus (Other)
KW  - Middle temporal gyrus (Other)
KW  - Novel word learning (Other)
KW  - Regional specificity (Other)
KW  - Temporal specificity (Other)
KW  - focal tDCS (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:38824804
DO  - DOI:10.1016/j.cortex.2024.05.004
UR  - https://pub.dzne.de/record/271063
ER  -