TY  - JOUR
AU  - Ahmed Ibnidris Elsiddig, Aliaa
AU  - Liaskos, Nektarios
AU  - Eldem, Ece
AU  - Gunn, Angus
AU  - Streffer, Johannes
AU  - Gold, Michael
AU  - Rea, Mike
AU  - Teipel, Stefan
AU  - Gardiol, Alejandra
AU  - Boccardi, Marina
TI  - Facilitating the use of the target product profile in academic research: a systematic review.
JO  - Journal of translational medicine
VL  - 22
IS  - 1
SN  - 1479-5876
CY  - London
PB  - BioMed Central
M1  - DZNE-2024-00936
SP  - 693
PY  - 2024
AB  - The Target Product Profile (TPP) is a tool used in industry to guide development strategies by addressing user needs and fostering effective communication among stakeholders. However, they are not frequently used in academic research, where they may be equally useful. This systematic review aims to extract the features of accessible TPPs, to identify commonalities and facilitate their integration in academic research methodology.We searched peer-reviewed papers published in English developing TPPs for different products and health conditions in four biomedical databases. Interrater agreement, computed on random abstract and paper sets (Cohen's Kappa; percentage agreement with zero tolerance) was > 0.91. We interviewed experts from industry contexts to gain insight on the process of TPP development, and extracted general and specific features on TPP use and structure.138 papers were eligible for data extraction. Of them, 92
KW  - Academia
KW  - Humans
KW  - Biomedical Research
KW  - Methodology (Other)
KW  - Quality by design (Other)
KW  - TPP (Other)
KW  - Target product profile (Other)
KW  - Translational methods (Other)
KW  - Translational research (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39075460
C2  - pmc:PMC11288132
DO  - DOI:10.1186/s12967-024-05476-1
UR  - https://pub.dzne.de/record/271064
ER  -