TY - JOUR AU - Obrecht-Sturm, Denise AU - Schömig, Lena AU - Mynarek, Martin AU - Bison, Brigitte AU - Schwarz, Rudolf AU - Pietsch, Torsten AU - Pfister, Stefan M AU - Sill, Martin AU - Sturm, Dominik AU - Sahm, Felix AU - Kortmann, Rolf-Dieter AU - Gerber, Nicolas U AU - von Bueren, André O AU - Fleischhack, Gudrun AU - Schüller, Ulrich AU - Nussbaumer, Gunther AU - Benesch, Martin AU - Rutkowski, Stefan TI - Treatment response as surrogate to predict risk for disease progression in pediatric medulloblastoma with persistent magnetic resonance imaging lesions after first-line treatment. JO - Neuro-Oncology VL - 26 IS - 9 SN - 1522-8517 CY - Oxford PB - Oxford Univ. Press M1 - DZNE-2024-01108 SP - 1712 - 1722 PY - 2024 AB - This study aims at clarifying the impact of persistent residual lesions following first-line treatment for pediatric medulloblastoma.Data on 84 pediatric patients with medulloblastoma and persistent residual lesions on centrally reviewed magnetic resonance imaging (MRI) at the end of first-line therapy were analyzed.Twenty patients (23.8 KW - Humans KW - Medulloblastoma: diagnostic imaging KW - Medulloblastoma: pathology KW - Male KW - Child KW - Female KW - Magnetic Resonance Imaging: methods KW - Cerebellar Neoplasms: diagnostic imaging KW - Cerebellar Neoplasms: pathology KW - Disease Progression KW - Child, Preschool KW - Adolescent KW - Follow-Up Studies KW - Prognosis KW - Retrospective Studies KW - Survival Rate KW - Infant KW - Neoplasm, Residual: diagnostic imaging KW - Neoplasm, Residual: pathology KW - MRI (Other) KW - children (Other) KW - medulloblastoma (Other) KW - persistent residual disease (Other) LB - PUB:(DE-HGF)16 C6 - pmid:38578306 C2 - pmc:PMC11376455 DO - DOI:10.1093/neuonc/noae071 UR - https://pub.dzne.de/record/271966 ER -