000272337 001__ 272337
000272337 005__ 20240924164122.0
000272337 020__ $$a978-1-0716-4010-4 (print)
000272337 020__ $$a978-1-0716-4011-1 (electronic)
000272337 0247_ $$2doi$$a10.1007/978-1-0716-4011-1_5
000272337 0247_ $$2ISSN$$a0893-2336
000272337 0247_ $$2ISSN$$a1940-6045
000272337 037__ $$aDZNE-2024-01156
000272337 082__ $$a610
000272337 1001_ $$aRusakov, Dmitri$$b0$$eEditor
000272337 245__ $$aSynaptic Photodamage and Its Application to Study Microglia–Synapse Interactions In Vivo
000272337 260__ $$aNew York, NY$$bSpringer US$$c2024
000272337 29510 $$aFluorescence Imaging of the Brain / Rusakov, Dmitri (Editor) ; New York, NY : Springer US, 2024, Chapter 5 ; ISSN: 0893-2336=1940-6045 ; ISBN: 978-1-0716-4010-4=978-1-0716-4011-1 ; doi:10.1007/978-1-0716-4011-1
000272337 300__ $$a111 - 126
000272337 3367_ $$2ORCID$$aBOOK_CHAPTER
000272337 3367_ $$07$$2EndNote$$aBook Section
000272337 3367_ $$2DRIVER$$abookPart
000272337 3367_ $$2BibTeX$$aINBOOK
000272337 3367_ $$2DataCite$$aOutput Types/Book chapter
000272337 3367_ $$0PUB:(DE-HGF)7$$2PUB:(DE-HGF)$$aContribution to a book$$bcontb$$mcontb$$s1727166638_16291
000272337 4900_ $$aNeuromethods$$v209
000272337 520__ $$aMicroglia appeared as the major player in the remodeling of synapses under physiological and pathophysiological conditions, in particular during development, forgetting, and neuroinflammation. In this chapter, we describe in vivo two-photon photodamage of single synapses to induce microglia–synapse interactions. Application examples are provided to illustrate the advantages offered by this methodology for the spatiotemporal control of microglia engagement in synaptic remodeling. Direct observation of this process opens new possibilities to gain mechanistic insights into how microglia are involved in various neurological and psychiatric disorders.
000272337 536__ $$0G:(DE-HGF)POF4-351$$a351 - Brain Function (POF4-351)$$cPOF4-351$$fPOF IV$$x0
000272337 588__ $$aDataset connected to CrossRef Book Series, Journals: pub.dzne.de
000272337 7001_ $$0P:(DE-2719)9001455$$aCangalaya, Carla$$b1$$eFirst author$$udzne
000272337 7001_ $$0P:(DE-2719)2810577$$aDityatev, Alexander$$b2$$eLast author$$udzne
000272337 773__ $$a10.1007/978-1-0716-4011-1_5
000272337 8564_ $$uhttps://pub.dzne.de/record/272337/files/DZNE-2024-01156_Restricted.pdf
000272337 8564_ $$uhttps://pub.dzne.de/record/272337/files/DZNE-2024-01156_Restricted.pdf?subformat=pdfa$$xpdfa
000272337 909CO $$ooai:pub.dzne.de:272337$$pVDB
000272337 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9001455$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE
000272337 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2810577$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b2$$kDZNE
000272337 9131_ $$0G:(DE-HGF)POF4-351$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vBrain Function$$x0
000272337 9141_ $$y2024
000272337 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-08-19
000272337 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-08-19
000272337 9201_ $$0I:(DE-2719)1310007$$kAG Dityatev$$lMolecular Neuroplasticity$$x0
000272337 980__ $$acontb
000272337 980__ $$aVDB
000272337 980__ $$aI:(DE-2719)1310007
000272337 980__ $$aUNRESTRICTED