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| 001 | 272338 | ||
| 005 | 20240924164122.0 | ||
| 020 | _ | _ | |a 978-1-0716-4010-4 (print) |
| 020 | _ | _ | |a 978-1-0716-4011-1 (electronic) |
| 024 | 7 | _ | |a 10.1007/978-1-0716-4011-1_2 |2 doi |
| 024 | 7 | _ | |a 0893-2336 |2 ISSN |
| 024 | 7 | _ | |a 1940-6045 |2 ISSN |
| 037 | _ | _ | |a DZNE-2024-01157 |
| 082 | _ | _ | |a 610 |
| 100 | 1 | _ | |a Rusakov, Dmitri |b 0 |e Editor |
| 245 | _ | _ | |a Quantitative Optical Analysis of Astrocytic Ca2+ Signaling |
| 260 | _ | _ | |a New York, NY |c 2024 |b Springer US |
| 295 | 1 | 0 | |a Fluorescence Imaging of the Brain / Rusakov, Dmitri (Editor) ; New York, NY : Springer US, 2024, Chapter 2 ; ISSN: 0893-2336=1940-6045 ; ISBN: 978-1-0716-4010-4=978-1-0716-4011-1 ; doi:10.1007/978-1-0716-4011-1 |
| 300 | _ | _ | |a 21 - 57 |
| 336 | 7 | _ | |a BOOK_CHAPTER |2 ORCID |
| 336 | 7 | _ | |a Book Section |0 7 |2 EndNote |
| 336 | 7 | _ | |a bookPart |2 DRIVER |
| 336 | 7 | _ | |a INBOOK |2 BibTeX |
| 336 | 7 | _ | |a Output Types/Book chapter |2 DataCite |
| 336 | 7 | _ | |a Contribution to a book |b contb |m contb |0 PUB:(DE-HGF)7 |s 1727171183_3424 |2 PUB:(DE-HGF) |
| 490 | 0 | _ | |a Neuromethods |v 209 |
| 520 | _ | _ | |a Ca2+ signaling of astrocytes plays a central role in the physiology and pathophysiology of these non-neuronal cells in the brain. Decades of research have revealed the heterogeneity of astrocytic Ca2+ signals and how they are triggered, how they propagate, what mechanisms sustain them, and what their downstream effects are on the cellular, network, and behavioral level. Imaging of astrocytic Ca2+ signals has been and is at the center of this research. It has benefited from the development of novel indicators, of new imaging techniques, and of new analytical approaches. This enabled researchers to uncover a striking diversity of Ca2+ signals regarding, for instance, their spatial and temporal patterns, which have been linked to the operation of brain circuits. When interpreting recorded Ca2+ signals it needs to be considered how cellular changes of [Ca2+] are reflected by the recorded fluorescence of a Ca2+ indicator, what available and useful analytical approaches are, and what their advantages and limitations are. Here, we provide an overview of quantitative Ca2+ imaging in astrocytes by covering theoretical and practical aspects of Ca2+ imaging, available indicators and strategies, and toolboxes for image data analysis. |
| 536 | _ | _ | |a 351 - Brain Function (POF4-351) |0 G:(DE-HGF)POF4-351 |c POF4-351 |f POF IV |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef Book Series, Journals: pub.dzne.de |
| 700 | 1 | _ | |a Zeug, André |b 1 |
| 700 | 1 | _ | |a Unichenko, Petr |b 2 |
| 700 | 1 | _ | |a Müller, Franziska E. |b 3 |
| 700 | 1 | _ | |a Henneberger, Christian |0 P:(DE-2719)2811625 |b 4 |e Last author |u dzne |
| 773 | _ | _ | |a 10.1007/978-1-0716-4011-1_2 |
| 856 | 4 | _ | |u https://pub.dzne.de/record/272338/files/DZNE-2024-01157_Restricted.pdf |
| 856 | 4 | _ | |u https://pub.dzne.de/record/272338/files/DZNE-2024-01157_Restricted.pdf?subformat=pdfa |x pdfa |
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| 910 | 1 | _ | |a Deutsches Zentrum für Neurodegenerative Erkrankungen |0 I:(DE-588)1065079516 |k DZNE |b 4 |6 P:(DE-2719)2811625 |
| 913 | 1 | _ | |a DE-HGF |b Gesundheit |l Neurodegenerative Diseases |1 G:(DE-HGF)POF4-350 |0 G:(DE-HGF)POF4-351 |3 G:(DE-HGF)POF4 |2 G:(DE-HGF)POF4-300 |4 G:(DE-HGF)POF |v Brain Function |x 0 |
| 914 | 1 | _ | |y 2024 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |d 2023-08-19 |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |d 2023-08-19 |
| 920 | 1 | _ | |0 I:(DE-2719)1013029 |k AG Henneberger |l Synaptic and Glial Plasticity |x 0 |
| 980 | _ | _ | |a contb |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-2719)1013029 |
| 980 | _ | _ | |a UNRESTRICTED |
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