TY  - JOUR
AU  - Neher, Jonas J
AU  - Simons, Mikael
TI  - Protective lifelines: Tunneling nanotubes connect neurons and microglia.
JO  - Neuron
VL  - 112
IS  - 18
SN  - 0896-6273
CY  - New York, NY
PB  - Elsevier
M1  - DZNE-2024-01167
SP  - 2991 - 2993
PY  - 2024
AB  - Tunneling nanotubes (TNTs) facilitate the exchange of intracellular cargo between cells. In this issue of Neuron, Scheiblich et al.1 reveal that TNTs selectively mediate the bidirectional transfer of cytoplasmic protein aggregates from neurons to microglia and mitochondria from microglia to neurons, thereby preserving neuronal health.
KW  - Microglia: metabolism
KW  - Neurons: metabolism
KW  - Animals
KW  - Humans
KW  - Nanotubes
KW  - Cell Communication: physiology
KW  - Mitochondria: metabolism
KW  - Cell Membrane Structures
KW  - Tunneling Nanotubes (NLM Chemicals)
LB  - PUB:(DE-HGF)16
C6  - pmid:39326386
DO  - DOI:10.1016/j.neuron.2024.07.027
UR  - https://pub.dzne.de/record/272486
ER  -