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001     272486
005     20241001164214.0
024 7 _ |a 10.1016/j.neuron.2024.07.027
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024 7 _ |a 0896-6273
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024 7 _ |a 1097-4199
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037 _ _ |a DZNE-2024-01167
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100 1 _ |a Neher, Jonas J
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245 _ _ |a Protective lifelines: Tunneling nanotubes connect neurons and microglia.
260 _ _ |a New York, NY
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520 _ _ |a Tunneling nanotubes (TNTs) facilitate the exchange of intracellular cargo between cells. In this issue of Neuron, Scheiblich et al.1 reveal that TNTs selectively mediate the bidirectional transfer of cytoplasmic protein aggregates from neurons to microglia and mitochondria from microglia to neurons, thereby preserving neuronal health.
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650 _ 7 |a Tunneling Nanotubes
|2 NLM Chemicals
650 _ 2 |a Microglia: metabolism
|2 MeSH
650 _ 2 |a Neurons: metabolism
|2 MeSH
650 _ 2 |a Animals
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650 _ 2 |a Humans
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650 _ 2 |a Nanotubes
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650 _ 2 |a Cell Communication: physiology
|2 MeSH
650 _ 2 |a Mitochondria: metabolism
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650 _ 2 |a Cell Membrane Structures
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700 1 _ |a Simons, Mikael
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773 _ _ |a 10.1016/j.neuron.2024.07.027
|g Vol. 112, no. 18, p. 2991 - 2993
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|t Neuron
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787 0 _ |a Scheiblich, Hannah et.al.
|d New York, NY : Elsevier, 2024
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|t Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes.
856 4 _ |u https://pub.dzne.de/record/272486/files/DZNE-2024-01167_Restricted.pdf
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910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
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