000272879 001__ 272879 000272879 005__ 20250127091550.0 000272879 0247_ $$2pmid$$apmid:39219171 000272879 0247_ $$2doi$$a10.1002/mrm.30282 000272879 0247_ $$2ISSN$$a1522-2594 000272879 0247_ $$2ISSN$$a0740-3194 000272879 037__ $$aDZNE-2024-01295 000272879 082__ $$a610 000272879 1001_ $$0P:(DE-2719)9001610$$aNiesen, Svenja$$b0$$eFirst author$$udzne 000272879 245__ $$aSpiral 3DREAM sequence for fast whole‐brain B1 mapping 000272879 260__ $$aNew York, NY [u.a.]$$bWiley-Liss$$c2025 000272879 3367_ $$2DRIVER$$aarticle 000272879 3367_ $$2DataCite$$aOutput Types/Journal article 000272879 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1730284230_2966 000272879 3367_ $$2BibTeX$$aARTICLE 000272879 3367_ $$2ORCID$$aJOURNAL_ARTICLE 000272879 3367_ $$00$$2EndNote$$aJournal Article 000272879 520__ $$a This work demonstrates a new variant of the 3DREAM sequence for whole-brain B 1 + $$ {\mathrm{B}}_1^{+} $$ mapping employing a three-dimensional (3D) stack-of-spirals readout. The spiral readout reduces the echo train length after the STEAM preparation in order to overcome the significant blurring in STE* images due to the decreasing STE* signal with each excitation pulse.The 3DREAM sequence rapidly acquires two contrasts to calculate whole-brain flip angle maps. In the proposed spiral 3DREAM sequence, the Cartesian readout scheme is replaced by an accelerated 3D stack-of-spirals readout with a CAIPIRINHA sampling scheme. Phantom experiments were conducted to compare flip angle maps of the spiral 3DREAM sequence to a Cartesian 3DREAM sequence, an actual flip-angle-imaging (AFI) sequence, the dual-angle method, and the Bloch-Siegert shift method. Afterwards, the results were validated in vivo acquiring flip angle maps from five subjects.Flip angle maps of the spiral 3DREAM sequences showed high agreement with the reference methods both in phantom and in vivo experiments. Blurring in STE* images and flip angle maps was reduced compared to the Cartesian 3DREAM sequence.The spiral 3DREAM sequence utilizes a fast readout minimizing the echo train length of the imaging train. This reduces blurring in STE* images as well as the total acquisition time and increases the effective resolution of B 1 + $$ {\mathrm{B}}_1^{+} $$ maps. 000272879 536__ $$0G:(DE-HGF)POF4-354$$a354 - Disease Prevention and Healthy Aging (POF4-354)$$cPOF4-354$$fPOF IV$$x0 000272879 588__ $$aDataset connected to CrossRef, Journals: pub.dzne.de 000272879 650_2 $$2MeSH$$aHumans 000272879 650_2 $$2MeSH$$aImaging, Three-Dimensional: methods 000272879 650_2 $$2MeSH$$aBrain: diagnostic imaging 000272879 650_2 $$2MeSH$$aPhantoms, Imaging 000272879 650_2 $$2MeSH$$aAlgorithms 000272879 650_2 $$2MeSH$$aMagnetic Resonance Imaging: methods 000272879 650_2 $$2MeSH$$aReproducibility of Results 000272879 650_2 $$2MeSH$$aBrain Mapping: methods 000272879 650_2 $$2MeSH$$aImage Interpretation, Computer-Assisted: methods 000272879 650_2 $$2MeSH$$aImage Enhancement: methods 000272879 7001_ $$0P:(DE-2719)2814200$$aVeldmann, Marten$$b1 000272879 7001_ $$0P:(DE-2719)2812222$$aEhses, Philipp$$b2 000272879 7001_ $$0P:(DE-2719)2810538$$aStöcker, Tony$$b3$$eLast author 000272879 773__ $$0PERI:(DE-600)1493786-4$$a10.1002/mrm.30282$$gVol. 93, no. 1, p. 321 - 329$$n1$$p321 - 329$$tMagnetic resonance in medicine$$v93$$x1522-2594$$y2025 000272879 8564_ $$uhttps://pub.dzne.de/record/272879/files/DZNE-2024-01295.pdf$$yOpenAccess 000272879 8564_ $$uhttps://pub.dzne.de/record/272879/files/DZNE-2024-01295.pdf?subformat=pdfa$$xpdfa$$yOpenAccess 000272879 909CO $$ooai:pub.dzne.de:272879$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire 000272879 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)9001610$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b0$$kDZNE 000272879 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2814200$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b1$$kDZNE 000272879 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2812222$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b2$$kDZNE 000272879 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2810538$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b3$$kDZNE 000272879 9131_ $$0G:(DE-HGF)POF4-354$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vDisease Prevention and Healthy Aging$$x0 000272879 9141_ $$y2024 000272879 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bMAGN RESON MED : 2022$$d2023-10-21 000272879 915__ $$0LIC:(DE-HGF)CCBYNC4$$2HGFVOC$$aCreative Commons Attribution-NonCommercial CC BY-NC 4.0 000272879 915__ $$0StatID:(DE-HGF)3001$$2StatID$$aDEAL Wiley$$d2023-10-21$$wger 000272879 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)1030$$2StatID$$aDBCoverage$$bCurrent Contents - Life Sciences$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess 000272879 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)1110$$2StatID$$aDBCoverage$$bCurrent Contents - Clinical Medicine$$d2023-10-21 000272879 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2023-10-21$$wger 000272879 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2023-10-21 000272879 9201_ $$0I:(DE-2719)1013026$$kAG Stöcker$$lMR Physics$$x0 000272879 9201_ $$0I:(DE-2719)1040310$$kAG Reuter$$lArtificial Intelligence in Medicine$$x1 000272879 980__ $$ajournal 000272879 980__ $$aVDB 000272879 980__ $$aUNRESTRICTED 000272879 980__ $$aI:(DE-2719)1013026 000272879 980__ $$aI:(DE-2719)1040310 000272879 9801_ $$aFullTexts