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@ARTICLE{Niesen:272879,
author = {Niesen, Svenja and Veldmann, Marten and Ehses, Philipp and
Stöcker, Tony},
title = {{S}piral 3{DREAM} sequence for fast whole‐brain {B}1
mapping},
journal = {Magnetic resonance in medicine},
volume = {93},
number = {1},
issn = {1522-2594},
address = {New York, NY [u.a.]},
publisher = {Wiley-Liss},
reportid = {DZNE-2024-01295},
pages = {321 - 329},
year = {2025},
abstract = {This work demonstrates a new variant of the 3DREAM sequence
for whole-brain B 1 + $$ {\mathrm{B}}_1^{+} $$ mapping
employing a three-dimensional (3D) stack-of-spirals readout.
The spiral readout reduces the echo train length after the
STEAM preparation in order to overcome the significant
blurring in STE* images due to the decreasing STE* signal
with each excitation pulse.The 3DREAM sequence rapidly
acquires two contrasts to calculate whole-brain flip angle
maps. In the proposed spiral 3DREAM sequence, the Cartesian
readout scheme is replaced by an accelerated 3D
stack-of-spirals readout with a CAIPIRINHA sampling scheme.
Phantom experiments were conducted to compare flip angle
maps of the spiral 3DREAM sequence to a Cartesian 3DREAM
sequence, an actual flip-angle-imaging (AFI) sequence, the
dual-angle method, and the Bloch-Siegert shift method.
Afterwards, the results were validated in vivo acquiring
flip angle maps from five subjects.Flip angle maps of the
spiral 3DREAM sequences showed high agreement with the
reference methods both in phantom and in vivo experiments.
Blurring in STE* images and flip angle maps was reduced
compared to the Cartesian 3DREAM sequence.The spiral 3DREAM
sequence utilizes a fast readout minimizing the echo train
length of the imaging train. This reduces blurring in STE*
images as well as the total acquisition time and increases
the effective resolution of B 1 + $$ {\mathrm{B}}_1^{+} $$
maps.},
keywords = {Humans / Imaging, Three-Dimensional: methods / Brain:
diagnostic imaging / Phantoms, Imaging / Algorithms /
Magnetic Resonance Imaging: methods / Reproducibility of
Results / Brain Mapping: methods / Image Interpretation,
Computer-Assisted: methods / Image Enhancement: methods},
cin = {AG Stöcker / AG Reuter},
ddc = {610},
cid = {I:(DE-2719)1013026 / I:(DE-2719)1040310},
pnm = {354 - Disease Prevention and Healthy Aging (POF4-354)},
pid = {G:(DE-HGF)POF4-354},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:39219171},
doi = {10.1002/mrm.30282},
url = {https://pub.dzne.de/record/272879},
}