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000273018 1001_ $$00000-0002-9384-3474$$aWitt, Karsten$$b0
000273018 245__ $$aDiagnostics and treatment of impulse control disorders, psychosis and delirium: systemic review-based recommendations - guideline 'Parkinson's disease' of the German Society of Neurology.
000273018 260__ $$aHeidelberg$$bSpringer$$c2024
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000273018 520__ $$aImpulse control disorders (ICD), psychosis and delirium are part of the spectrum of behavioural changes associated with Parkinson's disease (PD). The diagnostic and therapeutic management of these rather complex neuropsychiatric conditions has been updated in the clinical guideline by the German Society of Neurology (DGN).Recommendations are based on a systematic literature reviews, other relevant guidelines and expert opinion.Patients receiving dopamine agonists (DA) therapy should be informed about the symptoms and risks of an ICD and should be routinely screened for ICD symptoms. In the presence of an ICD, DA should be reduced or discontinued and psychotherapeutic treatment may be considered. Non-oral therapies (levodopa/carbidopa intestinal gel infusion or deep brain stimulation) may also be an option for appropriate candidates. Psychosis in PD often has a gradual onset. Cognitive and affective disorders, psychiatric and medical comorbidities as well as polypharmacy are risk factors for a psychosis. Non-pharmacological treatments should be implemented as soon as possible and anti-parkinsonian medications should be adjusted/reduced if feasible. For psychosis associated with PD, quetiapine or clozapine should be used on an as-needed basis and for as short a time as is necessary, with safety monitoring. Delirium in PD may be underdiagnosed due to an overlap with chronic neuropsychiatric features of PD. Although transient by definition, delirium in PD can lead to permanent cognitive decline, motor impairment and increased mortality. Management of delirium includes pharmacological and non-pharmacological interventions.The updated guideline encompasses the evidence-based diagnostic, non-pharmacological and pharmacological management of ICD, psychosis and delirium in PD.
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000273018 650_7 $$2Other$$aDelirium
000273018 650_7 $$2Other$$aGuideline
000273018 650_7 $$2Other$$aImpulse control disorder
000273018 650_7 $$2Other$$aParkinson’s disease
000273018 650_7 $$2Other$$aPsychosis
000273018 650_7 $$2NLM Chemicals$$aAntiparkinson Agents
000273018 650_2 $$2MeSH$$aHumans
000273018 650_2 $$2MeSH$$aPsychotic Disorders: therapy
000273018 650_2 $$2MeSH$$aPsychotic Disorders: diagnosis
000273018 650_2 $$2MeSH$$aPsychotic Disorders: etiology
000273018 650_2 $$2MeSH$$aPsychotic Disorders: drug therapy
000273018 650_2 $$2MeSH$$aParkinson Disease: therapy
000273018 650_2 $$2MeSH$$aParkinson Disease: complications
000273018 650_2 $$2MeSH$$aParkinson Disease: diagnosis
000273018 650_2 $$2MeSH$$aDelirium: therapy
000273018 650_2 $$2MeSH$$aDelirium: diagnosis
000273018 650_2 $$2MeSH$$aDelirium: etiology
000273018 650_2 $$2MeSH$$aDisruptive, Impulse Control, and Conduct Disorders: etiology
000273018 650_2 $$2MeSH$$aDisruptive, Impulse Control, and Conduct Disorders: therapy
000273018 650_2 $$2MeSH$$aDisruptive, Impulse Control, and Conduct Disorders: diagnosis
000273018 650_2 $$2MeSH$$aGermany
000273018 650_2 $$2MeSH$$aSocieties, Medical: standards
000273018 650_2 $$2MeSH$$aNeurology: standards
000273018 650_2 $$2MeSH$$aPractice Guidelines as Topic: standards
000273018 650_2 $$2MeSH$$aAntiparkinson Agents: therapeutic use
000273018 650_2 $$2MeSH$$aAntiparkinson Agents: administration & dosage
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000273018 7001_ $$aHasan, Alkomiet$$b3
000273018 7001_ $$aEbersbach, Georg$$b4
000273018 7001_ $$aGroup, German Parkinson’s Guideline$$b5$$eCollaboration Author
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