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@ARTICLE{Salomoni:273927,
author = {Salomoni, Paolo},
title = {{U}nderstanding brain cancer and exploiting its
vulnerabilities.},
journal = {Molecular oncology},
volume = {18},
number = {12},
issn = {1574-7891},
address = {Hoboken, NJ},
publisher = {John Wiley $\&$ Sons, Inc.},
reportid = {DZNE-2024-01401},
pages = {2817 - 2821},
year = {2024},
abstract = {Brain cancer is one of the most devastating neoplasms
affecting both children and adults. Its dismal prognosis has
for long-time discouraged research in this area. However, in
the last 10-15 years remarkable progress has been made in
our understanding of brain cancer biology, thus showing
promise for the identification of new ways to treat these
tumors towards the improvement of patients' survival and
quality of life. This Thematic Issue on Brain cancers offers
a much needed and timely critical overview of the
fundamental discoveries in this area of research and which
of those are more promising for effective translation into
the clinic. Critically, many Reviews from this Issue also
provide discussion points on why the field has not
progressed as much as it had hoped to. It is important to
emphasize however that we are living in exciting times with
regards to our ability to translate fundamental findings
into the clinic thanks to the enormous technological
advances facilitating the study of cancer genomes and the
development of new drugs or repurposing existing agents.},
subtyp = {Editorial},
keywords = {Humans / Brain Neoplasms: genetics / Brain Neoplasms:
pathology / Brain Neoplasms: therapy / Animals},
cin = {AG Salomoni},
ddc = {610},
cid = {I:(DE-2719)1013032},
pnm = {352 - Disease Mechanisms (POF4-352)},
pid = {G:(DE-HGF)POF4-352},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:39582358},
pmc = {pmc:PMC11619798},
doi = {10.1002/1878-0261.13769},
url = {https://pub.dzne.de/record/273927},
}