TY  - JOUR
AU  - Bauer, Tobias
AU  - Olbrich, Simon
AU  - Groteklaes, Anne
AU  - Lehnen, Nils Christian
AU  - Zidan, Mousa
AU  - Lange, Annalena
AU  - Bisten, Justus
AU  - Walger, Lennart
AU  - Faber, Jennifer
AU  - Bruchhausen, Walter
AU  - Vollmuth, Philipp
AU  - Herrlinger, Ulrich
AU  - Radbruch, Alexander
AU  - Surges, Rainer
AU  - Sabir, Hemmen
AU  - Rüber, Theodor
TI  - Proof of concept: Portable ultra-low-field magnetic resonance imaging for the diagnosis of epileptogenic brain pathologies.
JO  - Epilepsia
VL  - 65
IS  - 12
SN  - 0013-9580
CY  - Oxford [u.a.]
PB  - Wiley-Blackwell
M1  - DZNE-2024-01433
SP  - 3607 - 3618
PY  - 2024
AB  - High-field magnetic resonance imaging (MRI) is a standard in the diagnosis of epilepsy. However, high costs and technical barriers have limited adoption in low- and middle-income countries. Even in high-income nations, many individuals with epilepsy face delays in undergoing MRI. Recent advancements in ultra-low-field (ULF) MRI technology, particularly the development of portable scanners, offer a promising solution to the limited accessibility of MRI. In this study, we present and evaluate the imaging capability of ULF MRI in detecting structural abnormalities typically associated with epilepsy and compare it to high-field MRI at 3 T.Data collection was conducted within 3 consecutive weeks at the University Hospital Bonn. Inclusion criteria were a minimum age of 18 years, diagnosed epilepsy, and clinical high-field MRI with abnormalities. We used a .064 T Swoop portable MR Imaging System. Both high-field MRI and ULF MRI scans were evaluated independently by two experienced neuroradiologists as part of their clinical routine, comparing pathology detection and diagnosis completeness.Twenty-three individuals with epilepsy were recruited. One subject presented with a dual pathology. Across the entire cohort, in 17 of 24 (71
KW  - Humans
KW  - Magnetic Resonance Imaging: methods
KW  - Epilepsy: diagnostic imaging
KW  - Male
KW  - Female
KW  - Adult
KW  - Young Adult
KW  - Middle Aged
KW  - Adolescent
KW  - Proof of Concept Study
KW  - Brain: diagnostic imaging
KW  - Brain: pathology
KW  - Epilepsy (Other)
KW  - Global Epileptology (Other)
KW  - Neuroimaging (Other)
KW  - Sustainability (Other)
KW  - limited ressources (Other)
LB  - PUB:(DE-HGF)16
C2  - pmc:PMC11647431
C6  - pmid:39470733
DO  - DOI:10.1111/epi.18171
UR  - https://pub.dzne.de/record/274005
ER  -