%0 Journal Article
%A Xu, Peng
%A Estrada Leon, Edgar Santiago
%A Etteldorf, Rika
%A Liu, Dan
%A Shahid, Mohammad
%A Zeng, Weiyi
%A Früh, Deborah
%A Reuter, Martin
%A Breteler, Monique
%A Aziz, N. Ahmad
%T Hypothalamic volume is associated with age, sex and cognitive function across lifespan: a comparative analysis of two large population-based cohort studies.
%J EBioMedicine
%V 111
%@ 2352-3964
%C Amsterdam [u.a.]
%I Elsevier
%M DZNE-2025-00003
%P 105513
%D 2024
%X Emerging findings indicate that the hypothalamus, the body's principal homeostatic centre, plays a crucial role in modulating cognition, but comprehensive population-based studies are lacking.We used cross-sectional data from the Rhineland Study (N = 5812, 55.2 ± 13.6 years, 58
%K Humans
%K Female
%K Male
%K Middle Aged
%K Cognition: physiology
%K Hypothalamus
%K Aged
%K Magnetic Resonance Imaging
%K Adult
%K Cohort Studies
%K Organ Size
%K Longevity
%K Sex Factors
%K Age Factors
%K Neuropsychological Tests
%K Cross-Sectional Studies
%K Aging: physiology
%K Age-associated cognitive decline (Other)
%K Brain imaging (Other)
%K Cognitive function (Other)
%K Cortisol (Other)
%K Hypothalamus (Other)
%K Sexual dimorphism (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%2 pmc:PMC11732039
%$ pmid:39708426
%R 10.1016/j.ebiom.2024.105513
%U https://pub.dzne.de/record/274021