TY  - JOUR
AU  - Xu, Peng
AU  - Estrada Leon, Edgar Santiago
AU  - Etteldorf, Rika
AU  - Liu, Dan
AU  - Shahid, Mohammad
AU  - Zeng, Weiyi
AU  - Früh, Deborah
AU  - Reuter, Martin
AU  - Breteler, Monique
AU  - Aziz, N. Ahmad
TI  - Hypothalamic volume is associated with age, sex and cognitive function across lifespan: a comparative analysis of two large population-based cohort studies.
JO  - EBioMedicine
VL  - 111
SN  - 2352-3964
CY  - Amsterdam [u.a.]
PB  - Elsevier
M1  - DZNE-2025-00003
SP  - 105513
PY  - 2024
AB  - Emerging findings indicate that the hypothalamus, the body's principal homeostatic centre, plays a crucial role in modulating cognition, but comprehensive population-based studies are lacking.We used cross-sectional data from the Rhineland Study (N = 5812, 55.2 ± 13.6 years, 58
KW  - Humans
KW  - Female
KW  - Male
KW  - Middle Aged
KW  - Cognition: physiology
KW  - Hypothalamus
KW  - Aged
KW  - Magnetic Resonance Imaging
KW  - Adult
KW  - Cohort Studies
KW  - Organ Size
KW  - Longevity
KW  - Sex Factors
KW  - Age Factors
KW  - Neuropsychological Tests
KW  - Cross-Sectional Studies
KW  - Aging: physiology
KW  - Age-associated cognitive decline (Other)
KW  - Brain imaging (Other)
KW  - Cognitive function (Other)
KW  - Cortisol (Other)
KW  - Hypothalamus (Other)
KW  - Sexual dimorphism (Other)
LB  - PUB:(DE-HGF)16
C2  - pmc:PMC11732039
C6  - pmid:39708426
DO  - DOI:10.1016/j.ebiom.2024.105513
UR  - https://pub.dzne.de/record/274021
ER  -