Home > Publications Database > How the brain impacts the heart: lessons from ischaemic stroke and other neurological disorders. > print

001     275907
005     20250411100212.0
024 7 _ |a 10.1136/heartjnl-2024-324173
|2 doi
024 7 _ |a pmid:39515993
|2 pmid
024 7 _ |a 0007-0769
|2 ISSN
024 7 _ |a 1355-6037
|2 ISSN
024 7 _ |a 1468-201X
|2 ISSN
024 7 _ |a altmetric:170329649
|2 altmetric
037 _ _ |a DZNE-2025-00140
041 _ _ |a English
082 _ _ |a 610
100 1 _ |a Stengl, Helena
|0 P:(DE-2719)9003150
|b 0
|e First author
245 _ _ |a How the brain impacts the heart: lessons from ischaemic stroke and other neurological disorders.
260 _ _ |a London
|c 2025
|b BMJ Publ. Group
336 7 _ |a article
|2 DRIVER
336 7 _ |a Output Types/Journal article
|2 DataCite
336 7 _ |a Journal Article
|b journal
|m journal
|0 PUB:(DE-HGF)16
|s 1744358491_5312
|2 PUB:(DE-HGF)
|x Review Article
336 7 _ |a ARTICLE
|2 BibTeX
336 7 _ |a JOURNAL_ARTICLE
|2 ORCID
336 7 _ |a Journal Article
|0 0
|2 EndNote
500 _ _ |a ISSN 1468-201X not unique: **2 hits**.
520 _ _ |a Cardiovascular alterations are common in patients who had ischaemic stroke, haemorrhagic stroke and other acute brain disorders such as seizures. These cardiac complications are important drivers of morbidity and mortality and comprise blood-based detection of cardiomyocyte damage, ECG changes, heart failure and arrhythmia. Recently, the concept of a distinct 'stroke-heart syndrome' has been formulated as a pathophysiological framework for poststroke cardiac complications. The concept considers cardiac sequelae after stroke to be the result of a stroke-induced disturbance of the brain-heart axis. In this review, we describe the spectrum of cardiac changes secondary to ischaemic stroke and other acute brain disorders. Furthermore, we focus on Takotsubo syndrome secondary to acute brain disorders as a model disease of disturbed brain-heart interaction. Finally, we aim to provide an overview of the anatomical and functional links between the brain and the heart, with emphasis on the autonomic network and the role of inflammation. Given the clinical relevance of the deleterious impact of acute brain injury on the heart, we call for clinical awareness and for starting joint efforts combining expertise of neurology and cardiology to identify specific therapeutic interventions.
536 _ _ |a 353 - Clinical and Health Care Research (POF4-353)
|0 G:(DE-HGF)POF4-353
|c POF4-353
|f POF IV
|x 0
588 _ _ |a Dataset connected to CrossRef, PubMed, , Journals: pub.dzne.de
650 _ 7 |a Arrhythmias, Cardiac
|2 Other
650 _ 7 |a Biomarkers
|2 Other
650 _ 7 |a Cardiovascular Diseases
|2 Other
650 _ 7 |a Inflammation
|2 Other
650 _ 7 |a Stroke
|2 Other
650 _ 2 |a Humans
|2 MeSH
650 _ 2 |a Ischemic Stroke: physiopathology
|2 MeSH
650 _ 2 |a Ischemic Stroke: etiology
|2 MeSH
650 _ 2 |a Brain: physiopathology
|2 MeSH
650 _ 2 |a Heart: physiopathology
|2 MeSH
650 _ 2 |a Takotsubo Cardiomyopathy: physiopathology
|2 MeSH
650 _ 2 |a Takotsubo Cardiomyopathy: etiology
|2 MeSH
650 _ 2 |a Takotsubo Cardiomyopathy: diagnosis
|2 MeSH
650 _ 2 |a Heart Diseases: etiology
|2 MeSH
650 _ 2 |a Heart Diseases: physiopathology
|2 MeSH
700 1 _ |a Poller, Wolfram C
|b 1
700 1 _ |a Di Vece, Davide
|0 0009-0006-4116-3596
|b 2
700 1 _ |a Templin, Christian
|b 3
700 1 _ |a Endres, Matthias
|0 P:(DE-2719)2811033
|b 4
|u dzne
700 1 _ |a Nolte, Christian H
|b 5
700 1 _ |a Scheitz, Jan F
|0 P:(DE-2719)9001514
|b 6
773 _ _ |a 10.1136/heartjnl-2024-324173
|g Vol. 111, no. 3, p. heartjnl-2024-324173 -
|0 PERI:(DE-600)2378689-9
|n 3
|p 99 - 108
|t British heart journal
|v 111
|y 2025
|x 0007-0769
856 4 _ |u https://pub.dzne.de/record/275907/files/DZNE-2025-00140_Restricted.pdf
856 4 _ |u https://pub.dzne.de/record/275907/files/DZNE-2025-00140_Restricted.pdf?subformat=pdfa
|x pdfa
909 C O |p VDB
|o oai:pub.dzne.de:275907
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 0
|6 P:(DE-2719)9003150
910 1 _ |a Deutsches Zentrum für Neurodegenerative Erkrankungen
|0 I:(DE-588)1065079516
|k DZNE
|b 4
|6 P:(DE-2719)2811033
913 1 _ |a DE-HGF
|b Gesundheit
|l Neurodegenerative Diseases
|1 G:(DE-HGF)POF4-350
|0 G:(DE-HGF)POF4-353
|3 G:(DE-HGF)POF4
|2 G:(DE-HGF)POF4-300
|4 G:(DE-HGF)POF
|v Clinical and Health Care Research
|x 0
914 1 _ |y 2025
915 _ _ |a National-Konsortium
|0 StatID:(DE-HGF)0430
|2 StatID
|d 2023-04-25
|w ger
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0300
|2 StatID
|b Medline
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0199
|2 StatID
|b Clarivate Analytics Master Journal List
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1190
|2 StatID
|b Biological Abstracts
|d 2023-04-25
915 _ _ |a WoS
|0 StatID:(DE-HGF)0113
|2 StatID
|b Science Citation Index Expanded
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0150
|2 StatID
|b Web of Science Core Collection
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1050
|2 StatID
|b BIOSIS Previews
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1110
|2 StatID
|b Current Contents - Clinical Medicine
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)1030
|2 StatID
|b Current Contents - Life Sciences
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0160
|2 StatID
|b Essential Science Indicators
|d 2023-04-25
915 _ _ |a JCR
|0 StatID:(DE-HGF)0100
|2 StatID
|b HEART : 2021
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0200
|2 StatID
|b SCOPUS
|d 2023-04-25
915 _ _ |a DBCoverage
|0 StatID:(DE-HGF)0600
|2 StatID
|b Ebsco Academic Search
|d 2023-04-25
915 _ _ |a Peer Review
|0 StatID:(DE-HGF)0030
|2 StatID
|b ASC
|d 2023-04-25
915 _ _ |a IF >= 5
|0 StatID:(DE-HGF)9905
|2 StatID
|b HEART : 2021
|d 2023-04-25
920 1 _ |0 I:(DE-2719)1811005
|k AG Endres
|l Interdisciplinary Dementia Research
|x 0
980 _ _ |a journal
980 _ _ |a VDB
980 _ _ |a I:(DE-2719)1811005
980 _ _ |a UNRESTRICTED

LibraryCollectionCLSMajorCLSMinorLanguageAuthor
Marc 21