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@ARTICLE{Xu:276118,
author = {Xu, Marshall and Ribeiro, Fernanda L. and Barth, Markus and
Bernier, Michaël and Bollmann, Steffen and Chatterjee,
Soumick and Cognolato, Francesco and Gulban, Omer F. and
Itkyal, Vaibhavi and Liu, Siyu and Mattern, Hendrik and
Polimeni, Jonathan R. and Shaw, Thomas B. and Speck, Oliver
and Bollmann, Saskia},
title = {{V}essel{B}oost: {A} {P}ython {T}oolbox for {S}mall {B}lood
{V}essel {S}egmentation in {H}uman {M}agnetic {R}esonance
{A}ngiography {D}ata},
journal = {Aperture neuro},
volume = {4},
issn = {2957-3963},
address = {Roseville},
publisher = {Organization for Human Brain Mapping},
reportid = {DZNE-2025-00199},
pages = {10.52294/001c.123217},
year = {2024},
abstract = {Magnetic resonance angiography (MRA) performed at
ultra-high magnetic field provides a unique opportunity to
study the arteries of the living human brain at the
mesoscopic level. From this, we can gain new insights into
the brain’s blood supply and vascular disease affecting
small vessels. However, for quantitative characterization
and precise representation of human angioarchitecture to,
for example, inform blood-flow simulations, detailed
segmentations of the smallest vessels are required. Given
the success of deep learning-based methods in many
segmentation tasks, we explore their application to
high-resolution MRA data and address the difficulty of
obtaining large data sets of correctly and comprehensively
labelled data. We introduce VesselBoost, a vessel
segmentation toolbox, which utilizes deep learning and
imperfect training labels for accurate vasculature
segmentation. To enhance the segmentation models’
robustness and accuracy, VesselBoost employs an innovative
data augmentation technique, which captures the resemblance
of vascular structures across scales by zooming in or out on
input image patches—virtually creating diverse scale
vascular data. This approach enables detailed vascular
segmentation and ensures the model’s ability to generalize
across various scales of vascular structures.},
cin = {AG Speck / AG Schreiber},
cid = {I:(DE-2719)1340009 / I:(DE-2719)1310010},
pnm = {353 - Clinical and Health Care Research (POF4-353)},
pid = {G:(DE-HGF)POF4-353},
typ = {PUB:(DE-HGF)16},
doi = {10.52294/001c.123217},
url = {https://pub.dzne.de/record/276118},
}