%0 Journal Article
%A Haeusler, Karl Georg
%A Tütüncü, Serdar
%A Fiessler, Cornelia
%A Jawad-Ul-Qamar, Muhammad
%A Kunze, Claudia
%A Schurig, Johannes
%A Dietzel, Joanna
%A Krämer, Michael
%A Petzold, Gabor C
%A Royl, Georg
%A Helberg, Torsten
%A Thomalla, Götz
%A Nabavi, Darius G
%A Röther, Joachim
%A Laufs, Ulrich
%A Veltkamp, Roland
%A Heuschmann, Peter U
%A Kirchhof, Paulus
%A Olma, Manuel C
%A Endres, Matthias
%T Excessive Supraventricular Ectopic Activity in Patients With Acute Ischemic Stroke Is Associated With Atrial Fibrillation Detection Within 24 Months After Stroke: A Predefined Analysis of the MonDAFIS Study.
%J Journal of the American Heart Association
%V 14
%N 2
%@ 2047-9980
%C New York, NY
%I Association
%M DZNE-2025-00231
%P e034512
%D 2025
%X Excessive supraventricular ectopic activity (ESVEA) is regarded as a risk marker for later atrial fibrillation (AF) detection.The investigator-initiated, prospective, open, multicenter MonDAFIS (Impact of Standardized Monitoring for Detection of Atrial Fibrillation in Ischemic Stroke) study randomized 3465 patients with acute ischemic stroke without known AF 1:1 to usual diagnostic procedures for AF detection or additive Holter monitoring in hospital for up to 7 days, analyzed in a core laboratory. Secondary study objectives include the comparison of recurrent stroke, myocardial infarction, major bleeding, and all-cause death within 24 months in patients with ESVEA (defined as ectopic supraventricular beats ≥480/day or atrial runs of 10-29 seconds or both) versus patients with newly diagnosed AF versus patients without ESVEA or AF (non-ESVEA/AF), randomized to the intervention group. Overall, 1435 (84.8
%K Humans
%K Atrial Fibrillation: diagnosis
%K Atrial Fibrillation: physiopathology
%K Atrial Fibrillation: complications
%K Female
%K Male
%K Aged
%K Ischemic Stroke: diagnosis
%K Ischemic Stroke: mortality
%K Ischemic Stroke: physiopathology
%K Ischemic Stroke: etiology
%K Electrocardiography, Ambulatory: methods
%K Prospective Studies
%K Time Factors
%K Middle Aged
%K Atrial Premature Complexes: diagnosis
%K Atrial Premature Complexes: physiopathology
%K Recurrence
%K Risk Factors
%K Aged, 80 and over
%K ECG (Other)
%K atrial fibrillation (Other)
%K atrial run (Other)
%K death (Other)
%K stroke (Other)
%K supraventricular ectopy (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39791425
%R 10.1161/JAHA.123.034512
%U https://pub.dzne.de/record/276159