TY  - JOUR
AU  - Haeusler, Karl Georg
AU  - Tütüncü, Serdar
AU  - Fiessler, Cornelia
AU  - Jawad-Ul-Qamar, Muhammad
AU  - Kunze, Claudia
AU  - Schurig, Johannes
AU  - Dietzel, Joanna
AU  - Krämer, Michael
AU  - Petzold, Gabor C
AU  - Royl, Georg
AU  - Helberg, Torsten
AU  - Thomalla, Götz
AU  - Nabavi, Darius G
AU  - Röther, Joachim
AU  - Laufs, Ulrich
AU  - Veltkamp, Roland
AU  - Heuschmann, Peter U
AU  - Kirchhof, Paulus
AU  - Olma, Manuel C
AU  - Endres, Matthias
TI  - Excessive Supraventricular Ectopic Activity in Patients With Acute Ischemic Stroke Is Associated With Atrial Fibrillation Detection Within 24 Months After Stroke: A Predefined Analysis of the MonDAFIS Study.
JO  - Journal of the American Heart Association
VL  - 14
IS  - 2
SN  - 2047-9980
CY  - New York, NY
PB  - Association
M1  - DZNE-2025-00231
SP  - e034512
PY  - 2025
AB  - Excessive supraventricular ectopic activity (ESVEA) is regarded as a risk marker for later atrial fibrillation (AF) detection.The investigator-initiated, prospective, open, multicenter MonDAFIS (Impact of Standardized Monitoring for Detection of Atrial Fibrillation in Ischemic Stroke) study randomized 3465 patients with acute ischemic stroke without known AF 1:1 to usual diagnostic procedures for AF detection or additive Holter monitoring in hospital for up to 7 days, analyzed in a core laboratory. Secondary study objectives include the comparison of recurrent stroke, myocardial infarction, major bleeding, and all-cause death within 24 months in patients with ESVEA (defined as ectopic supraventricular beats ≥480/day or atrial runs of 10-29 seconds or both) versus patients with newly diagnosed AF versus patients without ESVEA or AF (non-ESVEA/AF), randomized to the intervention group. Overall, 1435 (84.8
KW  - Humans
KW  - Atrial Fibrillation: diagnosis
KW  - Atrial Fibrillation: physiopathology
KW  - Atrial Fibrillation: complications
KW  - Female
KW  - Male
KW  - Aged
KW  - Ischemic Stroke: diagnosis
KW  - Ischemic Stroke: mortality
KW  - Ischemic Stroke: physiopathology
KW  - Ischemic Stroke: etiology
KW  - Electrocardiography, Ambulatory: methods
KW  - Prospective Studies
KW  - Time Factors
KW  - Middle Aged
KW  - Atrial Premature Complexes: diagnosis
KW  - Atrial Premature Complexes: physiopathology
KW  - Recurrence
KW  - Risk Factors
KW  - Aged, 80 and over
KW  - ECG (Other)
KW  - atrial fibrillation (Other)
KW  - atrial run (Other)
KW  - death (Other)
KW  - stroke (Other)
KW  - supraventricular ectopy (Other)
LB  - PUB:(DE-HGF)16
C6  - pmid:39791425
DO  - DOI:10.1161/JAHA.123.034512
UR  - https://pub.dzne.de/record/276159
ER  -