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000276486 1001_ $$0P:(DE-2719)9000494$$aBoekholt, Melanie$$b0$$eFirst author$$udzne
000276486 245__ $$aSupporting older people with cognitive impairment during and after hospital stays with intersectoral care management (intersec-CM)-results of a randomised clinical trial.
000276486 260__ $$aOxford$$bOxford Univ. Press$$c2025
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000276486 520__ $$aThe transition from hospital to primary care is a risk factor for negative health outcomes in people with cognitive impairment.To test the effectiveness of intersectoral care management during the transition from hospital to primary care on repeated admission to hospital, functionality and institutionalisation in people with cognitive impairment.Longitudinal multisite randomised controlled trial with two arms (care as usual and intersectoral care management) and two follow-ups 3 and 12 months after discharge.Three hospitals in two different primary care regions in Germany.n = 401 people with cognitive impairment: community-dwelling, age 70+. Randomised into control (n = 192) or intervention (n = 209).Primary outcomes for the study after 3 months: admission to hospital, physical and instrumental functionality. Primary outcome after 12 months: institutionalisation, physical and instrumental functionality. Secondary outcomes: health-related quality of life, depressive symptoms, cognitive status and frailty. Statistical analyses include descriptive analyses as well as univariate and multivariate regression models for all outcomes.There was no statistically significant effect of the intervention on hospital admission and activities of daily living after 3 months, as well as on institutionalisation and activities of daily living after 12 months. There were significantly fewer participants in the intervention group readmitted to the hospital 12 months after discharge.Analyses show a significant effect on health-related quality of life 3 months and 12 months after discharge. Depressive symptoms were significantly less likely in the intervention group 3 months after discharge. No effects on cognition or frailty.Intersectoral care management supports people with cognitive impairment during discharge and transition. Even though we were not able to show an impact of the intervention on the chosen primary outcomes everyday functionality and institutionalisation, the effects on health-related quality of life, hospital admission rate and mental health are solid indicators for an improved individual situation.ClinicalTrials.gov, NCT03359408; https://clinicaltrials.gov/ct2/show/NCT03359408.
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000276486 650_7 $$2Other$$aGermany
000276486 650_7 $$2Other$$acognitive impairment
000276486 650_7 $$2Other$$adementia care management
000276486 650_7 $$2Other$$ahospital discharge
000276486 650_7 $$2Other$$aolder people
000276486 650_7 $$2Other$$arandomised controlled trial
000276486 650_2 $$2MeSH$$aHumans
000276486 650_2 $$2MeSH$$aMale
000276486 650_2 $$2MeSH$$aFemale
000276486 650_2 $$2MeSH$$aAged
000276486 650_2 $$2MeSH$$aCognitive Dysfunction: therapy
000276486 650_2 $$2MeSH$$aCognitive Dysfunction: psychology
000276486 650_2 $$2MeSH$$aQuality of Life
000276486 650_2 $$2MeSH$$aAged, 80 and over
000276486 650_2 $$2MeSH$$aGermany
000276486 650_2 $$2MeSH$$aActivities of Daily Living
000276486 650_2 $$2MeSH$$aPatient Discharge
000276486 650_2 $$2MeSH$$aPrimary Health Care
000276486 650_2 $$2MeSH$$aInstitutionalization
000276486 650_2 $$2MeSH$$aLongitudinal Studies
000276486 650_2 $$2MeSH$$aCognition
000276486 650_2 $$2MeSH$$aTime Factors
000276486 650_2 $$2MeSH$$aPatient Readmission
000276486 650_2 $$2MeSH$$aFrailty: therapy
000276486 650_2 $$2MeSH$$aFrailty: diagnosis
000276486 650_2 $$2MeSH$$aFrailty: psychology
000276486 7001_ $$aNikelski, Angela$$b1
000276486 7001_ $$0P:(DE-2719)2812380$$aSchumacher-Schönert, Fanny$$b2$$udzne
000276486 7001_ $$0P:(DE-2719)9000627$$aKracht, Friederike$$b3$$udzne
000276486 7001_ $$0P:(DE-2719)2259205$$aVollmar, Horst Christian$$b4
000276486 7001_ $$0P:(DE-2719)2000040$$aHoffmann, Wolfgang$$b5$$udzne
000276486 7001_ $$00000-0001-7623-3423$$aKreisel, Stefan Henner$$b6
000276486 7001_ $$0P:(DE-2719)2290613$$aThyrian, Jochen Rene$$b7$$eLast author$$udzne
000276486 773__ $$0PERI:(DE-600)2065766-3$$a10.1093/ageing/afaf011$$gVol. 54, no. 2, p. afaf011$$n2$$pafaf011$$tAge & ageing$$v54$$x0002-0729$$y2025
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