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000277982 1001_ $$aGuidetti, Matteo$$b0
000277982 245__ $$aIs physical therapy recommended for people with parkinson's disease treated with subthalamic deep brain stimulation? a delphi consensus study.
000277982 260__ $$aLondon$$bBioMed Central$$c2025
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000277982 520__ $$aAlthough deep brain stimulation of the subthalamic nucleus (STN-DBS) induces motor benefits in people with Parkinson's disease (PwPD), its effect on motor axial symptoms (e.g., postural instability, trunk posture alterations) and gait impairments (e.g., freezing of gait) is still ambiguous. Physical therapy (PT) effectively complements pharmacological treatment to improve postural stability, gait performance, and other dopamine-resistant symptoms (e.g. freezing of gait) in the general population with PD. Despite the positive potential of combined PT and STN-DBS surgery, scientific results are still lacking. We therefore involved worldwide leading experts on DBS and motor rehabilitation in PwPD in a consensus Delphi panel to define the current level of PT recommendation following STN-DBS surgery.After summarizing the few available findings through a systematic scoping review, we identified clinically and academically experienced DBS clinicians (n = 21) to discuss the challenges related to PT following STN-DBS. A 5-point Likert scale questionnaire was used and based on the results of the systematic review, thirty-nine questions were designed and submitted to the panel-half related to general considerations on PT following STN-DBS, and half related to PT treatments.Despite the low-to-moderate quality of data, the few available rehabilitation studies suggested that PT could improve dynamic and static balance, gait performance and posture in the population with PD receiving STN-DBS. Similarly, the panellists strongly agreed that PT might help improve motor symptoms and quality of life, and it may be prescribed to maximize the effects of stimulation. The experts agreed that physical therapists could be part of the multidisciplinary team taking care of the patients. Also, they agreed that conventional PT, but not massage or manual therapy, should be prescribed because of the specificity of STN-DBS implantation.Although RCT evidence is lacking, upon Delphi panel, PT for PwPD receiving STN-DBS can be potentially useful to maximize clinical improvement. However, more research is needed, with RCTs and well-designed studies. The rehabilitation and DBS community should expand this area of research to create guidelines for PT following STN-DBS.
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000277982 650_7 $$2Other$$aDBS
000277982 650_7 $$2Other$$aDeep brain stimulation
000277982 650_7 $$2Other$$aDelphi consensus
000277982 650_7 $$2Other$$aMotor rehabilitation
000277982 650_7 $$2Other$$aMovement disorders
000277982 650_7 $$2Other$$aNeuromodulation
000277982 650_7 $$2Other$$aParkinson’s disease
000277982 650_7 $$2Other$$aPhysical therapy
000277982 650_7 $$2Other$$aPhysiotherapy
000277982 650_2 $$2MeSH$$aHumans
000277982 650_2 $$2MeSH$$aParkinson Disease: rehabilitation
000277982 650_2 $$2MeSH$$aParkinson Disease: therapy
000277982 650_2 $$2MeSH$$aDeep Brain Stimulation: methods
000277982 650_2 $$2MeSH$$aDelphi Technique
000277982 650_2 $$2MeSH$$aSubthalamic Nucleus
000277982 650_2 $$2MeSH$$aPhysical Therapy Modalities
000277982 650_2 $$2MeSH$$aConsensus
000277982 7001_ $$aMarceglia, Sara$$b1
000277982 7001_ $$aBocci, Tommaso$$b2
000277982 7001_ $$aDuncan, Ryan$$b3
000277982 7001_ $$aFasano, Alfonso$$b4
000277982 7001_ $$aFoote, Kelly D$$b5
000277982 7001_ $$aHamani, Clement$$b6
000277982 7001_ $$aKrauss, Joachim K$$b7
000277982 7001_ $$0P:(DE-2719)2811089$$aKühn, Andrea A$$b8$$udzne
000277982 7001_ $$aLena, Francesco$$b9
000277982 7001_ $$aLimousin, Patricia$$b10
000277982 7001_ $$aLozano, Andres M$$b11
000277982 7001_ $$aMaiorana, Natale V$$b12
000277982 7001_ $$aModugno, Nicola$$b13
000277982 7001_ $$aMoro, Elena$$b14
000277982 7001_ $$aOkun, Michael S$$b15
000277982 7001_ $$aOliveri, Serena$$b16
000277982 7001_ $$aSantilli, Marco$$b17
000277982 7001_ $$aSchnitzler, Alfons$$b18
000277982 7001_ $$aTemel, Yasin$$b19
000277982 7001_ $$aTimmermann, Lars$$b20
000277982 7001_ $$aVisser-Vandewalle, Veerle$$b21
000277982 7001_ $$aVolkmann, Jens$$b22
000277982 7001_ $$aPriori, Alberto$$b23
000277982 773__ $$0PERI:(DE-600)2164377-5$$a10.1186/s12984-025-01616-w$$gVol. 22, no. 1, p. 80$$n1$$p80$$tJournal of neuroEngineering and rehabilitation$$v22$$x1743-0003$$y2025
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