000277992 001__ 277992
000277992 005__ 20250430100241.0
000277992 0247_ $$2doi$$a10.1016/j.chiabu.2025.107354
000277992 0247_ $$2pmid$$apmid:40081162
000277992 0247_ $$2ISSN$$a0145-2134
000277992 0247_ $$2ISSN$$a1873-7757
000277992 037__ $$aDZNE-2025-00519
000277992 041__ $$aEnglish
000277992 082__ $$a370
000277992 1001_ $$aKlinger-König, Johanna$$b0
000277992 245__ $$aThe age of onset and duration of childhood abuse: An extension of the childhood trauma screener.
000277992 260__ $$aAmsterdam [u.a.]$$bElsevier Science$$c2025
000277992 3367_ $$2DRIVER$$aarticle
000277992 3367_ $$2DataCite$$aOutput Types/Journal article
000277992 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1744616519_11312
000277992 3367_ $$2BibTeX$$aARTICLE
000277992 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000277992 3367_ $$00$$2EndNote$$aJournal Article
000277992 520__ $$aChildhood abuse is a significant risk factor for worse adult mental and physical health. Although reported as important moderators, only a few studies have analyzed the effects of the age of onset and duration of abuse, particularly including potential sex differences.To investigate the impact of timing and severity of childhood abuse on adult mental and physical health issues, with an emphasis on sex differences.Data from 2412 participants (52 % women, 28-89 years) of the general population.The Childhood Trauma Screener (CTS) was extended to assess the severity additionally to the age of onset and cumulative exposure across predefined age intervals of physical, emotional, and sexual childhood abuse. Associations with adult health behavior, mental health issues, and inflammatory markers were investigated using regression analyses, complemented by sex interactions.An earlier onset of emotional abuse was associated with lower resilience (b = -0.51, p = 0.034), whereas greater cumulative exposure to emotional abuse was associated with an earlier onset of depression (b = -4.53, p = 0.041) and more severe depressive symptoms (b = 0.94, p = 0.049). Effect directions differed between men and women for associations between the age of onset of emotional abuse and C-reactive protein levels (b = -0.03, p = 0.042) as well as the cumulative exposure of emotional abuse and fibrinogen levels (b = 0.04, p = 0.007).The findings underscore the significance of both severity and timing on adult health outcomes, with notable sex differences. These results support the need for targeted prevention programs that consider multiple maltreatment aspects, along with tailored interventions based on sex-specific vulnerabilities.
000277992 536__ $$0G:(DE-HGF)POF4-353$$a353 - Clinical and Health Care Research (POF4-353)$$cPOF4-353$$fPOF IV$$x0
000277992 588__ $$aDataset connected to CrossRef, PubMed, , Journals: pub.dzne.de
000277992 650_7 $$2Other$$aAlcohol
000277992 650_7 $$2Other$$aChildhood abuse
000277992 650_7 $$2Other$$aDepression
000277992 650_7 $$2Other$$aInflammation
000277992 650_7 $$2Other$$aResilience
000277992 650_7 $$2Other$$aSmoking
000277992 650_2 $$2MeSH$$aHumans
000277992 650_2 $$2MeSH$$aFemale
000277992 650_2 $$2MeSH$$aMale
000277992 650_2 $$2MeSH$$aAdult
000277992 650_2 $$2MeSH$$aMiddle Aged
000277992 650_2 $$2MeSH$$aAged
000277992 650_2 $$2MeSH$$aAge of Onset
000277992 650_2 $$2MeSH$$aAged, 80 and over
000277992 650_2 $$2MeSH$$aAdult Survivors of Child Abuse: psychology
000277992 650_2 $$2MeSH$$aAdult Survivors of Child Abuse: statistics & numerical data
000277992 650_2 $$2MeSH$$aChild Abuse: psychology
000277992 650_2 $$2MeSH$$aChild Abuse: statistics & numerical data
000277992 650_2 $$2MeSH$$aSex Factors
000277992 650_2 $$2MeSH$$aRisk Factors
000277992 650_2 $$2MeSH$$aChild
000277992 650_2 $$2MeSH$$aDepression
000277992 7001_ $$aKrause, Elischa$$b1
000277992 7001_ $$0P:(DE-2719)2810491$$aWittfeld, Katharina$$b2$$udzne
000277992 7001_ $$aFriedrich, Nele$$b3
000277992 7001_ $$aVölzke, Henry$$b4
000277992 7001_ $$0P:(DE-2719)2811781$$aGrabe, Hans J$$b5$$eLast author$$udzne
000277992 773__ $$0PERI:(DE-600)2004382-X$$a10.1016/j.chiabu.2025.107354$$gVol. 163, p. 107354 -$$p107354$$tChild abuse & neglect$$v163$$x0145-2134$$y2025
000277992 8564_ $$uhttps://pub.dzne.de/record/277992/files/DZNE-2025-00519.pdf$$yOpenAccess
000277992 8564_ $$uhttps://pub.dzne.de/record/277992/files/DZNE-2025-00519.pdf?subformat=pdfa$$xpdfa$$yOpenAccess
000277992 909CO $$ooai:pub.dzne.de:277992$$popenaire$$popen_access$$pVDB$$pdriver$$pdnbdelivery
000277992 9101_ $$0I:(DE-HGF)0$$6P:(DE-2719)2810491$$aExternal Institute$$b2$$kExtern
000277992 9101_ $$0I:(DE-588)1065079516$$6P:(DE-2719)2811781$$aDeutsches Zentrum für Neurodegenerative Erkrankungen$$b5$$kDZNE
000277992 9131_ $$0G:(DE-HGF)POF4-353$$1G:(DE-HGF)POF4-350$$2G:(DE-HGF)POF4-300$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bGesundheit$$lNeurodegenerative Diseases$$vClinical and Health Care Research$$x0
000277992 9141_ $$y2025
000277992 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-16
000277992 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-16
000277992 915__ $$0StatID:(DE-HGF)0130$$2StatID$$aDBCoverage$$bSocial Sciences Citation Index$$d2024-12-16
000277992 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2024-12-16
000277992 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bCHILD ABUSE NEGLECT : 2022$$d2024-12-16
000277992 915__ $$0StatID:(DE-HGF)1180$$2StatID$$aDBCoverage$$bCurrent Contents - Social and Behavioral Sciences$$d2024-12-16
000277992 915__ $$0LIC:(DE-HGF)CCBYNC4$$2HGFVOC$$aCreative Commons Attribution-NonCommercial CC BY-NC 4.0
000277992 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000277992 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2024-12-16
000277992 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2024-12-16
000277992 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2024-12-16
000277992 915__ $$0StatID:(DE-HGF)0420$$2StatID$$aNationallizenz$$d2024-12-16$$wger
000277992 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-16
000277992 9201_ $$0I:(DE-2719)5000001$$kAG Grabe$$lBiomarkers of Dementia in the General Population$$x0
000277992 980__ $$ajournal
000277992 980__ $$aVDB
000277992 980__ $$aUNRESTRICTED
000277992 980__ $$aI:(DE-2719)5000001
000277992 9801_ $$aFullTexts