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@ARTICLE{Becker:277997,
author = {Becker, Cornelia and Herschung, Lucas and Gomm, Willy and
Haenisch, Britta},
title = {{D}ementia diagnosis and prescription of antidementia
drugs: {A}n analysis of {G}erman claims data (2006-2016).},
journal = {Journal of Alzheimer's disease},
volume = {104},
number = {3},
issn = {1387-2877},
address = {Amsterdam},
publisher = {IOS Press},
reportid = {DZNE-2025-00524},
pages = {698 - 708},
year = {2025},
abstract = {BackgroundUse of claims data allows to analyze health
service characteristics of dementia, which is one of the
most frequent cognitive disorders in Germany and
worldwide.ObjectiveThe study aimed at describing the
variability in dementia diagnoses and in antidementia drug
prescription pattern.MethodsWe analyzed data from a
population-based sample of one of the largest German
statutory health insurances. The cohort included 30,403
patients with incident dementia diagnosis from 2006-2016. We
described frequencies, patterns, and interrelations of
diagnoses (Alzheimer's disease (AD), vascular dementia,
other specific dementia, unspecified dementia (UD),
antidementia drugs (ADD), and professional groups. We
described switches in diagnostic and medication patterns
between index quarter and following quarters, and evaluated
the prescriptions in relation to national
guidelines.ResultsA total of $87\%$ of patients received a
diagnosis of UD in at least one quarter of insurance. In the
quarter of incident diagnosis, $14\%$ of patients received
more than one diagnostic code of dementia, whereas over the
course of observation, the majority of patients received
more than one diagnostic code $(61\%).$ Most patients were
diagnosed by a general practitioner without involving a
specialist. All professional groups primarily made UD
diagnoses except specialists who mainly diagnosed AD.
Thirty-five percent of all patients and $67\%$ of AD
patients were prescribed an ADD at least
once.ConclusionsSpecialists made the most specific diagnoses
and prescribed most ADDs. A specialist consultation may be
advisable, but only $34\%$ of patients visited one. Many AD
patients might be left untreated due to underdiagnosis or
-treatment.},
keywords = {Humans / Germany: epidemiology / Dementia: diagnosis /
Dementia: drug therapy / Dementia: epidemiology / Male /
Female / Aged / Aged, 80 and over / Nootropic Agents:
therapeutic use / Drug Prescriptions: statistics $\&$
numerical data / Middle Aged / Cohort Studies / Practice
Patterns, Physicians': statistics $\&$ numerical data /
Insurance Claim Review / Alzheimer Disease: drug therapy /
Alzheimer Disease: diagnosis / Alzheimer Disease:
epidemiology / Alzheimer's disease (Other) / aged (Other) /
drugs (Other) / epidemiology (Other) / general practice
(Other) / Nootropic Agents (NLM Chemicals)},
cin = {AG Hänisch},
ddc = {610},
cid = {I:(DE-2719)1013010},
pnm = {354 - Disease Prevention and Healthy Aging (POF4-354)},
pid = {G:(DE-HGF)POF4-354},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:40095481},
doi = {10.1177/13872877251319468},
url = {https://pub.dzne.de/record/277997},
}