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@ARTICLE{Bauer:278021,
      author       = {Bauer, Tobias and Sabir, Hemmen and Baumgartner, Tobias and
                      Rácz, Attila and Pukropski, Jan and Badr, Mostafa and
                      Olbrich, Simon and Lange, Annalena and Bisten, Justus and
                      Groteklaes, Anne and Lehnen, Nils C and Cendes, Fernando and
                      Radbruch, Alexander and Surges, Rainer and Rüber, Theodor},
      title        = {{P}ortable ultra-low-field magnetic resonance imaging
                      enables postictal seizure imaging.},
      journal      = {Epilepsia},
      volume       = {66},
      number       = {4},
      issn         = {0013-9580},
      address      = {Oxford [u.a.]},
      publisher    = {Wiley-Blackwell},
      reportid     = {DZNE-2025-00531},
      pages        = {e60-e65},
      year         = {2025},
      abstract     = {The detection of transient peri-ictal magnetic resonance
                      imaging (MRI) abnormalities has been variable after
                      epileptic seizures. The most common reason for this
                      variability is that abnormalities may disappear if the
                      interval between seizure and scan acquisition is prolonged
                      using conventional high-field systems. Here, we deployed a
                      portable ultra-low-field MRI system in the presurgical
                      evaluation at the bedside of individuals with epilepsy. We
                      hypothesized that this novel technology enables rapid
                      postictal scans and reliably shows focal peri-ictal MRI
                      abnormalities in the seizure onset zone. A .064-T Swoop
                      Portable MR Imaging System was used. Postictally, an axial
                      diffusion-weighted sequence was acquired. The interictal MRI
                      consisted of the diffusion-weighted and three-dimensional
                      T1-weighted sequences. Postictal-interictal difference maps
                      of diffusion-weighted volumes were calculated. Three
                      individuals were included. Two individuals with focal aware
                      seizures scanned 29 s and 19 min after the seizure,
                      respectively, showed focal restrictions in diffusivity in
                      the seizure onset zone, and a third individual scanned 5 h
                      45 min after a focal to bilateral tonic-clonic seizure
                      showed global restrictions of diffusivity. Portable
                      ultra-low-field MRI opens a new line of inquiry with the aim
                      to establish postictal seizure imaging as part of the
                      presurgical evaluation of people with epilepsy.},
      keywords     = {Humans / Seizures: diagnostic imaging / Male / Female /
                      Magnetic Resonance Imaging: instrumentation / Magnetic
                      Resonance Imaging: methods / Adult / Diffusion Magnetic
                      Resonance Imaging: methods / Diffusion Magnetic Resonance
                      Imaging: instrumentation / Young Adult /
                      Electroencephalography / Middle Aged / Brain: pathology /
                      cortical localization (Other) / diffusion imaging (Other) /
                      epilepsy surgery (Other) / functional neuroimaging (Other) /
                      global epileptology (Other)},
      cin          = {AG Radbruch / AG Stöcker / AG Sabir},
      ddc          = {610},
      cid          = {I:(DE-2719)5000075 / I:(DE-2719)1013026 /
                      I:(DE-2719)5000032},
      pnm          = {353 - Clinical and Health Care Research (POF4-353) / 354 -
                      Disease Prevention and Healthy Aging (POF4-354) / 352 -
                      Disease Mechanisms (POF4-352)},
      pid          = {G:(DE-HGF)POF4-353 / G:(DE-HGF)POF4-354 /
                      G:(DE-HGF)POF4-352},
      typ          = {PUB:(DE-HGF)16},
      pubmed       = {pmid:39962944},
      pmc          = {pmc:PMC11997907},
      doi          = {10.1111/epi.18273},
      url          = {https://pub.dzne.de/record/278021},
}