%0 Journal Article
%A Gernert, Jonathan A
%A Christmann, Tara
%A Kaufmann, Elisabeth
%A Delazer, Luisa
%A Kirsch, Isabel
%A Levin, Johannes
%A Schönecker, Sonja
%A Fietzek, Urban
%A Eulenburg, Peter Zu
%A Velten, Theresa
%A Gripshi, Marina
%A Parhofer, Klaus G
%A Maier, Esther M
%A Kümpfel, Tania
%A Lotz-Havla, Amelie S
%A Havla, Joachim
%T Characterization of Peripapillary Hyperreflective Ovoid Mass-like Structures in a Broad Spectrum of Neurologic Disorders.
%J Ophthalmology
%V 132
%N 5
%@ 0161-6420
%C Amsterdam [u.a.]
%I Elsevier
%M DZNE-2025-00565
%P 590 - 597
%D 2025
%X Peripapillary hyperreflective ovoid mass-like structures (PHOMSs) have been identified in ophthalmic and neurologic diseases. Because PHOMSs were found more frequently in these cohorts compared with healthy control participants, it is assumed that the presence of PHOMSs reflects a secondary disease marker of unknown significance. The extent to which disease-specific differences are reflected in PHOMSs has not yet been investigated sufficiently.Monocentric, retrospective study.We analyzed a large cohort of people with a broad spectrum of neurologic disorders, including neuroimmunologic diseases (NIDs; n = 237), epilepsy (n = 153), movement disorders (MDs; n = 44), intracranial hypertension (IH; n = 13), and inborn errors of metabolism (n = 90).We analyzed the prevalence, location, volume, and intensity of PHOMSs. Peripapillary hyperreflective ovoid mass-like structure volumes were correlated with demographic and other OCT parameters.Prevalence, location, volume, and intensity of PHOMSs.We identified PHOMSs in 7
%K Humans
%K Retrospective Studies
%K Male
%K Female
%K Adult
%K Tomography, Optical Coherence: methods
%K Middle Aged
%K Optic Disk: pathology
%K Nervous System Diseases: diagnosis
%K Nervous System Diseases: complications
%K Young Adult
%K Aged
%K Adolescent
%K Child
%K Neurologic disorders (Other)
%K OCT (Other)
%K PHOMS (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:39675637
%R 10.1016/j.ophtha.2024.12.013
%U https://pub.dzne.de/record/278074