%0 Journal Article
%A Talevi, Valentina
%A Lee, Hang-mao
%A Liu, Dan
%A Beyer, Marc D
%A Salomoni, Paolo
%A Breteler, Monique M B
%A Aziz, N Ahmad
%T Age and Sex Effects on Blood Retrotransposable Element Expression Levels: Findings From the Population-Based Rhineland Study.
%J Aging cell
%V 24
%N 8
%@ 1474-9718
%C Oxford [u.a.]
%I Wiley-Blackwell
%M DZNE-2025-00592
%P e70092
%D 2025
%X Retrotransposable elements (RTEs) have been implicated in the pathogenesis of several age-associated diseases. Although model systems indicate that age- and sex-dependent loss of heterochromatin increases RTE expression, data from large human studies are lacking. Here we assessed the expression levels of 795 blood RTE subfamilies in 2467 participants of the population-based Rhineland Study. We found that the expression of more than 98
%K aging (Other)
%K biomarkers (Other)
%K heterochromatin (Other)
%K immune response (Other)
%K population‐based study (Other)
%K retrotransposable elements (Other)
%K sex‐differences (Other)
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40320676
%R 10.1111/acel.70092
%U https://pub.dzne.de/record/278552